Can a simple drug make kidney biopsies safer for transplant patients?

NCT ID NCT06622187

ENROLLING_BY_INVITATION Disease control Sponsor: Hospital de Clinicas de Porto Alegre Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether desmopressin, a drug that helps blood clot, can prevent bleeding during kidney biopsies in transplant patients. Researchers will give 96 high-risk patients either desmopressin or a placebo before the procedure and compare bleeding rates. The goal is to see if this approach reduces complications like major bleeding or hematomas.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Desmopressin (DDAVP)
What this could lead to: If it works, this could provide a simple way to reduce bleeding risk during kidney biopsies in transplant patients.
What could go wrong: This is a small, early-phase trial with only 96 participants, so results may not apply broadly. Desmopressin may not reduce bleeding significantly or could cause side effects like allergic reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Hemorrhage hemorrhagic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BLEEDING DESMOPRESSIN KIDNEY BIOPSY TRANSPLANT, KIDNEY

Contacts and locations

Locations

Hospital de Clinicas de Porto Alegre

Porto Alegre, Rio Grande do Sul, 90410000, Brazil

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