New Two-Drug attack tested for Tough-to-Treat bladder cancer

NCT ID NCT06524544

Recruiting now Disease control Sponsor: National Cancer Institute (NCI) Source: ClinicalTrials.gov ↗

Summary

This study is for people with advanced bladder cancer that has spread and has stopped responding to a common type of immunotherapy. It compares a new two-drug combination (pembrolizumab and sacituzumab govitecan) against standard chemotherapy. The goal is to see if the new combination helps patients live longer and better controls the cancer.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Abbott-Northwestern Hospital
RECRUITING

Minneapolis, Minnesota, 55407, United States

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Avera Cancer Institute
RECRUITING

Sioux Falls, South Dakota, 57105, United States

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Avera Cancer Institute - Mitchell
RECRUITING

Mitchell, South Dakota, 57301, United States

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Avera Cancer Institute at Marshall
RECRUITING

Marshall, Minnesota, 56258, United States

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Avera Cancer Institute at Yankton
RECRUITING

Yankton, South Dakota, 57078, United States

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BJC Outpatient Center at Sunset Hills
RECRUITING

Sunset Hills, Missouri, 63127, United States

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Benefis Sletten Cancer Institute
RECRUITING

Great Falls, Montana, 59405, United States

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Billings Clinic Cancer Center
RECRUITING

Billings, Montana, 59101, United States

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Bozeman Health Deaconess Hospital
RECRUITING

Bozeman, Montana, 59715, United States

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Cancer Care Specialists of Illinois - Decatur
RECRUITING

Decatur, Illinois, 62526, United States

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Carle BroMenn Medical Center
RECRUITING

Normal, Illinois, 61761, United States

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Carle Cancer Center
RECRUITING

Urbana, Illinois, 61801, United States

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Carle Cancer Institute Normal
RECRUITING

Normal, Illinois, 61761, United States

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Carle Physician Group-Effingham
RECRUITING

Effingham, Illinois, 62401, United States

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Carle Physician Group-Mattoon/Charleston
RECRUITING

Mattoon, Illinois, 61938, United States

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Carle at The Riverfront
RECRUITING

Danville, Illinois, 61832, United States

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Community Hospital of Anaconda
RECRUITING

Anaconda, Montana, 59711, United States

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Community Medical Center
RECRUITING

Missoula, Montana, 59804, United States

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Community Medical Center
RECRUITING

Toms River, New Jersey, 08755, United States

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Crossroads Cancer Center
RECRUITING

Effingham, Illinois, 62401, United States

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Decatur Memorial Hospital
RECRUITING

Decatur, Illinois, 62526, United States

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Duluth Clinic Ashland
RECRUITING

Ashland, Wisconsin, 54806, United States

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Essentia Health - Deer River Clinic
RECRUITING

Deer River, Minnesota, 56636, United States

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Essentia Health Cancer Center
RECRUITING

Duluth, Minnesota, 55805, United States

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Essentia Health Cancer Center-South University Clinic
RECRUITING

Fargo, North Dakota, 58103, United States

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Essentia Health Hibbing Clinic
RECRUITING

Hibbing, Minnesota, 55746, United States

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Essentia Health Saint Joseph's Medical Center
RECRUITING

Brainerd, Minnesota, 56401, United States

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Essentia Health Sandstone
RECRUITING

Sandstone, Minnesota, 55072, United States

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Essentia Health Virginia Clinic
RECRUITING

Virginia, Minnesota, 55792, United States

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FHCC Overlake
RECRUITING

Bellevue, Washington, 98004, United States

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FHCC at EvergreenHealth
RECRUITING

Kirkland, Washington, 98034, United States

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FHCC at Northwest Hospital
RECRUITING

Seattle, Washington, 98133, United States

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Fred Hutchinson Cancer Center
RECRUITING

Seattle, Washington, 98109, United States

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Hematology Oncology Associates of Fredericksburg Inc
RECRUITING

Fredericksburg, Virginia, 22408, United States

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IRMC Cancer Center
RECRUITING

Indiana, Pennsylvania, 15701, United States

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Kootenai Clinic Cancer Services - Post Falls
RECRUITING

Post Falls, Idaho, 83854, United States

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Kootenai Clinic Cancer Services - Sandpoint
RECRUITING

Sandpoint, Idaho, 83864, United States

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Kootenai Health - Coeur d'Alene
RECRUITING

Coeur d'Alene, Idaho, 83814, United States

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Mary Greeley Medical Center
RECRUITING

Ames, Iowa, 50010, United States

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McFarland Clinic - Ames
RECRUITING

Ames, Iowa, 50010, United States

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McFarland Clinic - Boone
SUSPENDED

Boone, Iowa, 50036, United States
McFarland Clinic - Jefferson
SUSPENDED

Jefferson, Iowa, 50129, United States
McFarland Clinic - Marshalltown
RECRUITING

Marshalltown, Iowa, 50158, United States

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McFarland Clinic - Trinity Cancer Center
RECRUITING

Fort Dodge, Iowa, 50501, United States

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Memorial Hospital East
RECRUITING

Shiloh, Illinois, 62269, United States

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Mercy Hospital
RECRUITING

Cedar Rapids, Iowa, 52403, United States

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Missouri Baptist Medical Center
RECRUITING

St Louis, Missouri, 63131, United States

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Missouri Baptist Sullivan Hospital
RECRUITING

Sullivan, Missouri, 63080, United States

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Monmouth Medical Center
RECRUITING

Long Branch, New Jersey, 07740, United States

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Oncology Associates at Mercy Medical Center
RECRUITING

Cedar Rapids, Iowa, 52403, United States

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Parkland Health Center - Farmington
RECRUITING

Farmington, Missouri, 63640, United States

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Penn State Milton S Hershey Medical Center
RECRUITING

Hershey, Pennsylvania, 17033-0850, United States

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Reading Hospital
RECRUITING

West Reading, Pennsylvania, 19611, United States

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Robert Wood Johnson University Hospital Somerset
RECRUITING

Somerville, New Jersey, 08876, United States

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Roswell Park Cancer Institute
RECRUITING

Buffalo, New York, 14263, United States

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Rutgers Cancer Institute of New Jersey
RECRUITING

New Brunswick, New Jersey, 08903, United States

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Rutgers New Jersey Medical School
RECRUITING

Newark, New Jersey, 07101, United States

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Saint Barnabas Medical Center
RECRUITING

Livingston, New Jersey, 07039, United States

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Saint Francis Medical Center
RECRUITING

Cape Girardeau, Missouri, 63703, United States

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Sainte Genevieve County Memorial Hospital
RECRUITING

Sainte Genevieve, Missouri, 63670, United States

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Siteman Cancer Center at Christian Hospital
RECRUITING

St Louis, Missouri, 63136, United States

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Siteman Cancer Center at Saint Peters Hospital
RECRUITING

City of Saint Peters, Missouri, 63376, United States

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Siteman Cancer Center at West County Hospital
RECRUITING

Creve Coeur, Missouri, 63141, United States

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Siteman Cancer Center-South County
RECRUITING

St Louis, Missouri, 63129, United States

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Southern Illinois University School of Medicine
RECRUITING

Springfield, Illinois, 62702, United States

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Springfield Clinic
RECRUITING

Springfield, Illinois, 62702, United States

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Springfield Memorial Hospital
RECRUITING

Springfield, Illinois, 62781, United States

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Stony Brook University Medical Center
RECRUITING

Stony Brook, New York, 11794, United States

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The James Graham Brown Cancer Center at University of Louisville
RECRUITING

Louisville, Kentucky, 40202, United States

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Trinity Health IHA Medical Group Hematology Oncology - Brighton
RECRUITING

Brighton, Michigan, 48114, United States

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Trinity Health IHA Medical Group Hematology Oncology - Canton
RECRUITING

Canton, Michigan, 48188, United States

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Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
RECRUITING

Chelsea, Michigan, 48118, United States

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Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
RECRUITING

Ypsilanti, Michigan, 48197, United States

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Trinity Health Saint Joseph Mercy Oakland Hospital
RECRUITING

Pontiac, Michigan, 48341, United States

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Trinity Health Saint Mary Mercy Livonia Hospital
RECRUITING

Livonia, Michigan, 48154, United States

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UC Irvine Health/Chao Family Comprehensive Cancer Center
RECRUITING

Orange, California, 92868, United States

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UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
RECRUITING

Irvine, California, 92612, United States

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UF Health Cancer Institute - Gainesville
RECRUITING

Gainesville, Florida, 32610, United States

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UPMC Cancer Center-Washington
RECRUITING

Washington, Pennsylvania, 15301, United States

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UPMC Cancer Centers - Arnold Palmer Pavilion
RECRUITING

Greensburg, Pennsylvania, 15601, United States

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UPMC Hillman Cancer Center - Monroeville
RECRUITING

Monroeville, Pennsylvania, 15146, United States

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UPMC Hillman Cancer Center Erie
RECRUITING

Erie, Pennsylvania, 16505, United States

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UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion
RECRUITING

Mechanicsburg, Pennsylvania, 17050, United States

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UPMC Pinnacle Cancer Center/Community Osteopathic Campus
RECRUITING

Harrisburg, Pennsylvania, 17109, United States

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UPMC-Passavant Hospital
RECRUITING

Pittsburgh, Pennsylvania, 15237, United States

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University of Michigan Health - Sparrow Lansing
RECRUITING

Lansing, Michigan, 48912, United States

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University of Pittsburgh Cancer Institute (UPCI)
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States

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University of Vermont Medical Center
RECRUITING

Burlington, Vermont, 05401, United States

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University of Vermont and State Agricultural College
RECRUITING

Burlington, Vermont, 05405, United States

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University of Washington Medical Center - Montlake
RECRUITING

Seattle, Washington, 98195, United States

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UofL Health Medical Center Northeast
RECRUITING

Louisville, Kentucky, 40245, United States

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VCU Massey Cancer Center at Stony Point
RECRUITING

Richmond, Virginia, 23235, United States

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VCU Massey Comprehensive Cancer Center
RECRUITING

Richmond, Virginia, 23298, United States

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Virginia Cancer Institute
RECRUITING

Richmond, Virginia, 23229, United States

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Washington University School of Medicine
RECRUITING

St Louis, Missouri, 63110, United States

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West Virginia University Charleston Division
RECRUITING

Charleston, West Virginia, 25304, United States

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Conditions

Explore the condition pages connected to this study.

LOCALLY ADVANCED UROTHELIAL CARCINOMA METASTATIC UROTHELIAL CARCINOMA UNRESECTABLE UROTHELIAL CARCINOMA