Stem cell heart patch could be lifeline for failing hearts

NCT ID NCT04396899

Recruiting now Disease control Sponsor: University Medical Center Goettingen Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests a patch made from stem cells that is implanted onto the heart to help it pump better. It is for people with severe heart failure who cannot have a heart transplant. The study will check if the patch is safe and if it improves heart function and symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: engineered heart muscle (EHM) made from stem cells
What this could lead to: If it works, this could offer a new treatment option for people with advanced heart failure who have no other options, potentially improving heart function and quality of life.
What could go wrong: This is an early-phase trial with only 53 participants, so results may not apply to everyone. Risks include arrhythmias, immune rejection, and the procedure itself may not improve outcomes.

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Conditions

The condition(s) this trial relates to.

heart failure systolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Herz- und Diabeteszentrum Nordrhein-Westfalen
NOT_YET_RECRUITING

Bad Oeynhausen, North Rhine-Westphalia, 32545, Germany

Contact
University Medical Center Göttingen
RECRUITING

Göttingen, Lower Saxony, 37075, Germany

Contact
University Medical Center Schleswig-Holstein
RECRUITING

Lübeck, Schleswig-Holstein, 23562, Germany

Contact

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