New implant could help fight opioid addiction
NCT ID NCT06216132
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage study tested a new implant that slowly releases naltrexone, a medication used to treat opioid use disorder. The implant is placed under the skin and left for three months. The trial involved 16 healthy adults to check safety and how the drug enters the bloodstream. It is a first step toward a potential treatment that could help people stay on medication without daily pills or injections.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
naltrexone implant (extended-release naltrexone in a biodegradable implant)
What this could lead to
If successful, this implant could provide a long-lasting, steady-dose treatment option for opioid use disorder, potentially improving adherence and reducing relapse risk.
What could go wrong
This is a very early Phase 1 safety study in only 16 healthy adults, not people with opioid use disorder. It does not test effectiveness, and the implant requires insertion and removal procedures.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for OPIOID USE DISORDER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
JBR Clinical Research
Salt Lake City, Utah, 84107, United States