Can a simple blood test help ICU doctors use antibiotics wisely?
NCT ID NCT07481773
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a biomarker signature (BV score) can help doctors decide when to use antibiotics for ICU patients. About 1,200 adults in intensive care who started antibiotics within the past 72 hours will be randomly assigned to have their treatment guided by the biomarker plus clinical judgment, or by clinical judgment alone. The goal is to see if the biomarker approach leads to better patient outcomes and less unnecessary antibiotic use.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Biomarker-signature supported antibiotic treatment recommendation (diagnostic test)
What this could lead to
If successful, this could help doctors make better antibiotic decisions in ICUs, reducing side effects and antibiotic resistance while improving patient outcomes.
What could go wrong
This is an early-stage study focused on decision-making, not a new drug. The biomarker may not reliably distinguish bacterial from non-bacterial infections, and results may not apply to all ICU patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Montreal General Hospital
RECRUITINGMontreal, Quebec, H3G 1A4, Canada
Contact Email: •••••@•••••
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Research Institute McGill University Health Centre
RECRUITINGMontreal, Quebec, H4A3J1, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Research Institute of McGill University Health Center (RI-MUHC)
RECRUITINGMontreal, Quebec, H4A 3J1, Canada
Contact Email: •••••@•••••
Contact
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Royal Victoria Hospital
RECRUITINGMontreal, Quebec, H4A 3J1, Canada
Contact Email: •••••@•••••