Blood tests could guide oxygen therapy for severe brain injury
NCT ID NCT04855396
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether certain proteins in the blood can help doctors monitor severe traumatic brain injury and predict who might benefit from hyperbaric oxygen therapy. Researchers will analyze blood samples from 150 patients already enrolled in a larger trial testing different doses of hyperbaric oxygen. The goal is to find reliable markers that could make future treatment more personalized and clinical trials more effective.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hyperbaric oxygen therapy
What this could lead to
If successful, this could help doctors tailor hyperbaric oxygen therapy to individual patients and make future clinical trials more efficient.
What could go wrong
This is an observational study that does not directly test a treatment. The findings may not lead to improved outcomes or may not apply to all patients.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Detroit Receiving Hospital
RECRUITINGDetroit, Michigan, 48201, United States
Contact
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Duke University Hospital
NOT_YET_RECRUITINGDurham, North Carolina, 27710, United States
Contact
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Hamilton General Hospital
SUSPENDEDHamilton, Ontario, L8L 2X2, Canada
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Hennepin County Medical Center
RECRUITINGMinneapolis, Minnesota, 55415, United States
Contact
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OSU Wexner Medical Center
SUSPENDEDColumbus, Ohio, 43210, United States
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St. Mary's Medical Center
SUSPENDEDWest Palm Beach, Florida, 33407, United States
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UCSD Medical Center - Hillcrest Hospital
RECRUITINGSan Diego, California, 92103, United States
Contact
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University of Iowa Hospitals & Clinics
RECRUITINGIowa City, Iowa, 52242, United States
Contact
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University of Kentucky Hospital
RECRUITINGLexington, Kentucky, 40536, United States
Contact
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University of Maryland Medical Center
RECRUITINGBaltimore, Maryland, 21201, United States
Contact
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University of Nebraska Medical Center
SUSPENDEDOmaha, Nebraska, 68198, United States