First human test of BIIB144 begins: safety first

NCT ID NCT07662148

Not yet recruiting Knowledge-focused Sponsor: Biogen Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is the first time the experimental drug BIIB144 is given to humans. Researchers want to see if a single dose is safe and how the body handles it. About 48 healthy adults will receive either BIIB144 or a placebo by IV. The results will help decide if and how to test the drug in people with certain diseases.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BIIB144

What this could lead to

If safe, this could pave the way for future studies of BIIB144 in people with specific diseases.

What could go wrong

This is a very early, first-in-human trial with only 48 healthy volunteers. The drug may cause side effects or not work as hoped in later studies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEALTHY VOLUNTEER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••