First human test of BIIB144 begins: safety first

NCT ID NCT07662148

First seen Jun 27, 2026 · Last updated Jul 28, 2026 · Updated 2 times

Summary

This study is the first time the experimental drug BIIB144 is given to humans. Researchers want to see if a single dose is safe and how the body handles it. About 48 healthy adults will receive either BIIB144 or a placebo by IV. The results will help decide if and how to test the drug in people with certain diseases.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
BIIB144
What this could lead to
If safe, this could pave the way for future studies of BIIB144 in people with specific diseases.
What could go wrong
This is a very early, first-in-human trial with only 48 healthy volunteers. The drug may cause side effects or not work as hoped in later studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Las Vegas Clinical Research Unit, PPD Development, LP

    RECRUITING

    Las Vegas, Nevada, 89113, United States

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