Can a global registry unlock the best way to treat tricky heart blockages?
NCT ID NCT05100992
First seen Aug 19, 2026 · Last updated Aug 20, 2026 · Updated 1 time
Summary
This study is a global registry that will collect information on how doctors treat coronary bifurcation lesions—blockages that occur where a major heart artery splits into a side branch. These are among the most challenging blockages to treat with stents. The registry will track the techniques used and the outcomes for about 4,000 patients undergoing this procedure, aiming to understand which strategies are most successful and improve future care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Percutaneous coronary intervention (PCI) - a procedure to open blocked heart arteries using stents
- What this could lead to
- If successful, this registry could identify which techniques work best for treating tricky bifurcation blockages, potentially improving outcomes and guiding future treatment guidelines.
- What could go wrong
- As an observational registry, it cannot prove which treatment is best, and results may be influenced by differences in patient populations and hospital practices.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 4,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2020
- Expected to finish
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Jan 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Subjects over 18 years of age and undergoing bifurcation percutaneous coronary intervention at each of the participating center.
- Ages
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18 years and older
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Over 18 years of age * undergoing bifurcation percutaneous coronary intervention
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Minneapolis Heart Institute Foundation
RECRUITINGMinneapolis, Minnesota, 55407, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Hospital-to-Home transitional cardiac rehabilitation as a transition from Centre-Based cardiac rehabilitation after cardiac surgery: a Single-Blind randomised controlled trial
- Opportunistic screening of coronary artery calcium on Non-Gated routine chest CT using artificial intelligence: retrospective external validation and clinical risk stratification
- AI heart scan software aims to spot dangerous blockages without invasive probes
- A shot of nicorandil before stenting might keep blood flowing
- Can personalized breathing settings protect lungs during heart surgery?