Experimental cancer drug trial halted early

NCT ID NCT06540066

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage study tested a new antibody drug (BGB-B3227) alone or with another drug (tislelizumab) in 35 people with advanced solid tumors. The goal was to check safety and find the right dose. The study was terminated early, so results are limited.

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Conditions

The condition(s) this trial relates to.

cancer metastatic malignant neoplasm Neoplasm Metastasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Affiliated Zhongshan Hospital of Fudan University

    Shanghai, Shanghai Municipality, 200032, China

  • Beijing Cancer Hospital

    Beijing, Beijing Municipality, 100142, China

  • Cancer Hospital Chinese Academy of Medical Sciences

    Beijing, Beijing Municipality, 100021, China

  • Fondazione Irccs Istituto Nazionale Dei Tumori

    Milan, 20133, Italy

  • Fondazione Policlinico Universitario Agostino Gemelli

    Roma, 00168, Italy

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601-1915, United States

  • Istituto Clinico Humanitas

    Rozzano, 20089, Italy

  • Istituto Europeo Di Oncologia

    Milan, 20141, Italy

  • Md Anderson Cancer Center

    Houston, Texas, 77030-3907, United States

  • Next Oncology

    Austin, Texas, 78758, United States

  • Usc Norris Comprehensive Cancer Center (Nccc)

    Los Angeles, California, 90089-1019, United States

  • Washington University in St Louis

    St Louis, Missouri, 63110-1010, United States