Could many heart patients ditch Beta-Blockers? new trial investigates

NCT ID NCT05081999

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether people with stable ischemic heart disease (but with normal heart pumping function and no ongoing chest pain or arrhythmias) can safely stop taking beta-blockers. About 59 participants will either continue or stop their beta-blocker and be followed for up to 4 years to compare heart events and quality of life. The goal is to see if stopping the drug reduces side effects without increasing risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

beta-blocker discontinuation

What this could lead to

If successful, this could show that many stable heart disease patients can safely stop taking beta-blockers, reducing side effects and medication burden.

What could go wrong

This is a small, early-phase pragmatic trial with only 59 participants, so results may not apply broadly. There is a risk that stopping beta-blockers could increase heart events.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder myocardial ischemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Alberta Hospital

    Edmonton, Alberta, T6G 2B7, Canada