Stent or no stent? new study tests best approach for leg artery disease

NCT ID NCT03776799

Ongoing Disease control Sponsor: University of Leipzig Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two treatments for complex blockages in the leg's main artery: one avoids stents by using a drug-coated balloon, the other uses a stent. About 120 people with peripheral arterial disease will be randomly assigned to one approach. The goal is to see which keeps the artery open longer and improves walking ability.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Drug-coated balloon (stent-avoiding) or drug-eluting/interwoven stent (stent-preferred)
What this could lead to: If successful, this could show that avoiding stents with drug-coated balloons works as well or better than stenting for complex leg artery blockages, potentially reducing the need for permanent implants.
What could go wrong: This is a small pilot study with only 120 participants, so results may not apply to everyone. Both approaches carry risks like re-blockage or need for repeat procedures.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIPHERAL ARTERIAL DISEASE

Contacts and locations

Locations

University Clinic Leipzig

Leipzig, Saxony, 04103, Germany

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Other studies related to the condition(s) this trial covers.