Natural compound berberine takes on Schizophrenia's hidden symptoms

NCT ID NCT07356765

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether berberine, a natural compound, can safely improve negative symptoms of schizophrenia—like low motivation and emotion—that current medications often miss. Researchers will give berberine or a placebo to 120 Han Chinese adults with stable schizophrenia and track changes in symptoms, gut bacteria, and inflammation. The goal is to find a new way to ease these challenging symptoms and improve daily life.

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Conditions

The condition(s) this trial relates to.

schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Tianjin Anding Hospital

    Tianjin, China