Can a plant compound tame PCOS symptoms?

NCT ID NCT07465575

Not yet recruiting Symptom relief Sponsor: Liaquat University of Medical & Health Sciences Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a daily berberine supplement (550 mg) can improve PCOS symptoms like excess hair growth, acne, and weight in 150 women aged 18-40. Participants are split into three groups: those not taking inositol, those already on inositol, and a control group receiving only lifestyle advice. The trial lasts 12 weeks and measures changes in hair scores, acne impact, and body mass index.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: berberine phytosome (a dietary supplement)
What this could lead to: If it works, this could point toward a natural supplement option to help manage PCOS symptoms like excess hair, acne, and weight gain.
What could go wrong: This is a small, early-stage trial with only 150 participants over 12 weeks. The supplement may not work better than lifestyle changes alone, and results may not apply to all women with PCOS.

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Conditions

The condition(s) this trial relates to.

polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POLYCYSTIC OVARY SYNDROME

Contacts and locations

Locations

University of Urbino Carlo Bo

Urbino, Italy

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