New asthma drug aims to heal damaged airways

NCT ID NCT03953300

Summary

This study is testing whether the drug benralizumab can reduce inflammation and improve the physical structure of the lungs in people with a severe type of asthma. It involves 75 adults whose asthma is not well-controlled despite using standard high-dose inhalers. Researchers will compare the drug to a placebo over 48 weeks, using lung scans and tissue samples to see if it helps repair the airways.

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Contacts and locations

Locations

  • Research Site

    Birmingham, Alabama, 35209, United States

  • Research Site

    Los Angeles, California, 90033, United States

  • Research Site

    Jacksonville, Florida, 32204, United States

  • Research Site

    Miami, Florida, 33166, United States

  • Research Site

    Snellville, Georgia, 30078, United States

  • Research Site

    Indianapolis, Indiana, 46268, United States

  • Research Site

    Iowa City, Iowa, 52242, United States

  • Research Site

    Kansas City, Kansas, 66160, United States

  • Research Site

    Ann Arbor, Michigan, 48109, United States

  • Research Site

    Bloomfield Hills, Michigan, 48301, United States

  • Research Site

    Rochester, Minnesota, 55905, United States

  • Research Site

    St Louis, Missouri, 63156, United States

  • Research Site

    Maspeth, New York, 11378, United States

  • Research Site

    New Bern, North Carolina, 28562, United States

  • Research Site

    Winston-Salem, North Carolina, 27104, United States

  • Research Site

    Pittsburgh, Pennsylvania, 15213, United States

  • Research Site

    Galveston, Texas, 77555, United States

  • Research Site

    Lewisville, Texas, 75067, United States

  • Research Site

    Mansfield, Texas, 76063, United States

  • Research Site

    Calgary, Alberta, T2N 4Z6, Canada

  • Research Site

    Aalborg, 9000, Denmark

  • Research Site

    Aarhus N, 8200, Denmark

  • Research Site

    Copenhagen, 2400, Denmark

  • Research Site

    Hvidovre, 2650, Denmark

  • Research Site

    Næstved, 4700, Denmark

  • Research Site

    Odense C, 5000, Denmark

  • Research Site

    Vejle, 7100, Denmark

  • Research Site

    Gothenburg, 413 45, Sweden

  • Research Site

    Lund, 22185, Sweden

  • Research Site

    Cambridge, CB2 2QQ, United Kingdom

  • Research Site

    Headington, OX3 9DU, United Kingdom

  • Research Site

    Leicester, LE3 9QP, United Kingdom

  • Research Site

    Liverpool, L7 8XP, United Kingdom

  • Research Site

    London, W1G 8HU, United Kingdom

  • Research Site

    Wythenshawe, M23 9LT, United Kingdom

Conditions

Explore the condition pages connected to this study.