New drug shows promise in reversing lung damage from severe asthma
NCT ID NCT03953300
First seen Jun 27, 2026 · Last updated Jul 29, 2026 · Updated 4 times
Summary
This study tests whether benralizumab can improve lung structure and function in people with severe eosinophilic asthma who still have symptoms despite standard treatments. About 75 adults aged 18-70 will receive either the drug or a placebo for 48 weeks, followed by a 4-week check-up. The goal is to see if the drug reduces airway inflammation and prevents long-term lung damage.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Birmingham, Alabama, 35209, United States
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Los Angeles, California, 90033, United States
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Jacksonville, Florida, 32204, United States
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Miami, Florida, 33166, United States
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Snellville, Georgia, 30078, United States
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Indianapolis, Indiana, 46268, United States
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Iowa City, Iowa, 52242, United States
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Kansas City, Kansas, 66160, United States
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Ann Arbor, Michigan, 48109, United States
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Bloomfield Hills, Michigan, 48301, United States
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Rochester, Minnesota, 55905, United States
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St Louis, Missouri, 63156, United States
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Maspeth, New York, 11378, United States
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New Bern, North Carolina, 28562, United States
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Winston-Salem, North Carolina, 27104, United States
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Pittsburgh, Pennsylvania, 15213, United States
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Galveston, Texas, 77555, United States
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Lewisville, Texas, 75067, United States
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Mansfield, Texas, 76063, United States
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Calgary, Alberta, T2N 4Z6, Canada
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Aalborg, 9000, Denmark
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Aarhus N, 8200, Denmark
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Copenhagen, 2400, Denmark
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Hvidovre, 2650, Denmark
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Næstved, 4700, Denmark
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Odense C, 5000, Denmark
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Vejle, 7100, Denmark
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Gothenburg, 413 45, Sweden
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Lund, 22185, Sweden
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Cambridge, CB2 2QQ, United Kingdom
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Headington, OX3 9DU, United Kingdom
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Leicester, LE3 9QP, United Kingdom
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Liverpool, L7 8XP, United Kingdom
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London, W1G 8HU, United Kingdom
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Wythenshawe, M23 9LT, United Kingdom
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Other studies related to the condition(s) this trial covers.
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