Can antidepressants rewire how older adults see the future?
NCT ID NCT07681492
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study investigates how depression and antidepressants influence the way older adults update their beliefs about future events. Researchers compare 31 patients aged 65+ with major depression who are switching antidepressants to 31 healthy volunteers of the same age. Participants complete a belief-updating task and mood assessments at the start and after 12 weeks of treatment, with weekly check-ins on expectations and mood.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could reveal how antidepressants change the way older adults update their beliefs about the future, potentially improving treatment approaches.
What could go wrong
This is a small observational study (62 participants) focused on understanding mechanisms, not testing a new treatment. Results may not apply broadly.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DEPRESSION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Sleep Quality in MS: Quality of Life & Depressio NCT07681037
- Mindfulness vs. Problem-Solving for Veterans' Me NCT06162741
- Anxiety/Depression & Asthma Attack Risk Model (NCT07679321)
- Mindfulness App for Parent Stress: NCT05444881
- Dementia Risk Score Tool for Depressed Older Adu NCT07676851
- Lifestyle Physical Activity for Women with Alcoh NCT04667520
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Centre Hospitalier Guillaume Regnier
NOT_YET_RECRUITINGRennes, 35700, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Centre Hospitalier Guillaume Régnier
RECRUITINGRennes, 35700, France
Contact Phone: •••-•••-•••• Email: •••••@•••••