Can a simple injection replace an IV for this myeloma drug?

NCT ID NCT07742527

First seen Aug 03, 2026 · Last updated Aug 04, 2026 · Updated 1 time

Summary

This trial is testing whether belantamab, a drug used for multiple myeloma, can be given as a quick injection under the skin instead of a slow drip into a vein. About 22 adults with multiple myeloma who are already on standard maintenance therapy will receive both forms in a crossover design, allowing direct comparison. The study measures how much of the drug reaches the blood, how long it stays there, and whether the injection is safe and well tolerated. If successful, this could make treatment more convenient without compromising effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
belantamab (an antibody-drug conjugate) given as a subcutaneous injection with recombinant human hyaluronidase PH20, compared with intravenous belantamab
What this could lead to
If the subcutaneous version works as well as the intravenous one, it could offer a more convenient way to deliver belantamab for multiple myeloma patients, potentially reducing clinic visits and improving comfort.
What could go wrong
This is an early-phase trial with only 22 participants, so results may not apply broadly. The subcutaneous formulation might not match the intravenous version in absorption or safety, and side effects could still emerge.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

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