New drug combo shows promise for advanced oral cancer before surgery

NCT ID NCT07545083

First seen Apr 30, 2026 · Last updated May 15, 2026 · Updated 2 times

Summary

This study tests whether giving two drugs—becotatug vedotin and pucotenlimab—before surgery can shrink advanced mouth or throat cancer. About 26 people with stage III or IVa cancer will receive the combination, then have surgery to remove any remaining tumor. The main goal is to see how many patients have most of their cancer killed by the drugs before surgery.

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Contacts and locations

Study contacts

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Conditions

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