Mouth bacteria may predict cancer treatment success
NCT ID NCT07111455
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at how the community of bacteria in the mouth changes in 32 people with advanced oral cancer after they receive a combination of chemotherapy and immunotherapy. Researchers want to see if these bacterial shifts relate to how well the tumor shrinks and to long-term survival. The goal is to find clues that could one day help personalize treatment for oral cancer patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- chemoimmunotherapy (chemotherapy plus immunotherapy)
- What this could lead to
- If successful, this could help doctors predict which oral cancer patients will respond best to chemoimmunotherapy, potentially guiding more personalized treatment.
- What could go wrong
- This is a small, early observational study with only 32 participants, so findings may not apply to all patients. It is designed to gather knowledge, not to test a new treatment directly.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Department of Stomatology, Zhujiang Hospital, Southern Medical University
RECRUITINGGuangzhou, Guangdong, China
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