Mouth bacteria may predict cancer treatment success

NCT ID NCT07111455

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at how the community of bacteria in the mouth changes in 32 people with advanced oral cancer after they receive a combination of chemotherapy and immunotherapy. Researchers want to see if these bacterial shifts relate to how well the tumor shrinks and to long-term survival. The goal is to find clues that could one day help personalize treatment for oral cancer patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

chemoimmunotherapy (chemotherapy plus immunotherapy)

What this could lead to

If successful, this could help doctors predict which oral cancer patients will respond best to chemoimmunotherapy, potentially guiding more personalized treatment.

What could go wrong

This is a small, early observational study with only 32 participants, so findings may not apply to all patients. It is designed to gather knowledge, not to test a new treatment directly.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

oral cavity squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Stomatology, Zhujiang Hospital, Southern Medical University

    RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••