New brain cancer drug targets tumors with EGFR mutations

NCT ID NCT06072586

First seen Nov 20, 2025 · Last updated May 01, 2026 · Updated 17 times

Summary

This study tests an experimental drug called BDTX-1535 in people with aggressive brain tumors (high-grade glioma or glioblastoma) that have specific changes in the EGFR gene. The drug is designed to block a growth signal that these tumors rely on. The study has two parts: first, it measures how much drug reaches the tumor during surgery; second, it finds the safest dose to use, possibly combined with standard radiation. About 82 participants will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chandler Regional Medical Center

    RECRUITING

    Chandler, Arizona, 85224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • St. Joseph's Hospital and Medical Center

    RECRUITING

    Phoenix, Arizona, 85013, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.