St. Joseph's Hospital And Medical Center, Phoenix

This study tests an experimental drug called BDTX-1535 in people with aggressive brain tumors (high-grade glioma or glioblastoma) that have specific changes in the EGFR gene. The drug is designed to block a growth signal that these tumors rely on. The study has two parts: first, …

This study tests whether siponimod, a drug used for multiple sclerosis, can safely slow brain shrinkage in people with mild Alzheimer's disease. About 105 participants will receive either the drug or a placebo for 12 months, then be monitored for 6 more months. The main goal is t…

This study is collecting blood samples, medical history, and other health information from 2,000 people with ALS and healthy volunteers over 2 years. The goal is to build a large database that researchers can use to better understand ALS and related diseases. No new treatments ar…

This study aims to collect detailed health information from people who have a family history of ALS but don't have symptoms themselves. Researchers will follow 600 participants for 3 years, collecting blood samples, speech recordings, and health questionnaires every 4 months. The…