New drug combo shows promise in early cancer trial

NCT ID NCT04196530

Completed Disease control Sponsor: Eikon Therapeutics Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tested a new immunotherapy drug called BDB001, alone or combined with atezolizumab (Tecentriq), in 40 adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety, find the best dose, and see if the combination could shrink tumors. Results will help decide if further testing is worthwhile.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: BDB001 (EIK1001) and atezolizumab (Tecentriq)
What this could lead to: If successful, this could point toward a new combination therapy for advanced solid tumors that have stopped responding to other treatments.
What could go wrong: This is an early Phase 1 trial with only 40 participants, focused on safety and dosing. It is too small and early to know if the combination will work or be safe for broader use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TUMOR, SOLID

Contacts and locations

Locations

Angeles Clinic

Los Angeles, California, 90025, United States
Florida Cancer Specialists

Sarasota, Florida, 34230, United States
NEXT Oncology

San Antonio, Texas, 78229, United States
South Texas Accelerated Research Therapeutics (START)

San Antonio, Texas, 78229, United States
Tennessee Oncology

Nashville, Tennessee, 37203, United States

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