New drug combo shows promise in early cancer trial

NCT ID NCT04196530

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tested a new immunotherapy drug called BDB001, alone or combined with atezolizumab (Tecentriq), in 40 adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety, find the best dose, and see if the combination could shrink tumors. Results will help decide if further testing is worthwhile.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BDB001 (EIK1001) and atezolizumab (Tecentriq)

What this could lead to

If successful, this could point toward a new combination therapy for advanced solid tumors that have stopped responding to other treatments.

What could go wrong

This is an early Phase 1 trial with only 40 participants, focused on safety and dosing. It is too small and early to know if the combination will work or be safe for broader use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Angeles Clinic

    Los Angeles, California, 90025, United States

  • Florida Cancer Specialists

    Sarasota, Florida, 34230, United States

  • NEXT Oncology

    San Antonio, Texas, 78229, United States

  • South Texas Accelerated Research Therapeutics (START)

    San Antonio, Texas, 78229, United States

  • Tennessee Oncology

    Nashville, Tennessee, 37203, United States