New pill may tame stubborn high blood pressure

NCT ID NCT06168409

Completed Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 22 times

Summary

This study tested a new drug called baxdrostat in 218 adults whose high blood pressure remained high despite taking three or more medications. Participants received either baxdrostat or a placebo daily for 12 weeks. The main goal was to see if baxdrostat could lower average blood pressure over 24 hours better than placebo.

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Contacts and locations

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Locations

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Surprise, Arizona, 85374, United States
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Hollywood, Florida, 33024, United States
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Lake Worth, Florida, 33467, United States
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Port Charlotte, Florida, 33952, United States
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Fort Wayne, Indiana, 46804, United States
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Lexington, Kentucky, 40503, United States
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The Bronx, New York, 10455, United States
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Greenville, North Carolina, 27834, United States
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Jacksonville, North Carolina, 28546, United States
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Kinston, North Carolina, 28504, United States
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New Bern, North Carolina, 28562, United States
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Wilmington, North Carolina, 28401, United States
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Langhorne, Pennsylvania, 19047, United States
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Brownsville, Texas, 78526, United States
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Corpus Christi, Texas, 78404, United States
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Lampasas, Texas, 76550, United States
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CABA, C1061, Argentina
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CABA, C1425AGC, Argentina
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Capital Federal, C1060ABN, Argentina
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Córdoba, X5003DCP, Argentina
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Lanús Este, B1824KAJ, Argentina
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Rosario, S2000PBJ, Argentina
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San Miguel de Tucumán, 4000, Argentina
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San Vicente, 5006, Argentina
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Clayton, 3168, Australia
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Perth, 6000, Australia
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Ghent, 9000, Belgium
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Sofia, 1527, Bulgaria
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Sofia, 1618, Bulgaria
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Sofia, 1680, Bulgaria
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Edmonton, Alberta, T6G 2C8, Canada
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North Vancouver, British Columbia, V7M 2H4, Canada
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Cambridge, Ontario, N1R 6V6, Canada
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Toronto, Ontario, M6G 1M2, Canada
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Waterloo, Ontario, N2T 0C1, Canada
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Chicoutimi, Quebec, G7H 7K9, Canada
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Terrebonne, Quebec, J6X 4P7, Canada
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Benešov, 256 01, Czechia
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Brandýs nad Labem, 250 01, Czechia
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Broumov, 55001, Czechia
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Louny, 440 01, Czechia
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Bad Homburg, 61348, Germany
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Berlin, 12203, Germany
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Frankfurt, 60590, Germany
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Kaiserslautern, 67655, Germany
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Athens, 11527, Greece
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Attica, 11527, Greece
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Thessaloniki, 54642, Greece
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Budapest, 1115, Hungary
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Budapest, 1148, Hungary
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Kalocsa, 6300, Hungary
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Nyíregyháza, 4400, Hungary
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Pécs, 7635, Hungary
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Kota Bharu, 15586, Malaysia
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Muar town, 84000, Malaysia
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Sarawak Miri, 98000, Malaysia
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Angeles City, 2009, Philippines
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Iloilo City, 5000, Philippines
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Bialystok, 15-540, Poland
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Gdansk, 80-214, Poland
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Krakow, 30-688, Poland
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Lodz, 91-002, Poland
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Poznan, 61-848, Poland
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Warsaw, 04-628, Poland
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Riyadh, 11426, Saudi Arabia
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Riyadh, 11462, Saudi Arabia
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Brezno, 977 01, Slovakia
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Košice, 04022, Slovakia
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Svidník, 08901, Slovakia
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Cape Town, 7500, South Africa
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Durban, 4001, South Africa
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Barcelona, 08003, Spain
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Barcelona, 08036, Spain
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Madrid, 28040, Spain
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Madrid, 28041, Spain
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Santa Coloma de Gramenet, 08923, Spain
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Terrassa (Barcelona), 08221, Spain
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Valencia, 46010, Spain
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New Taipei City, 220, Taiwan
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Taipei, 11217, Taiwan
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Taoyuan, 333, Taiwan
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Bangkok, 10330, Thailand
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Bangkok, 10400, Thailand
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Bangkok, 10700, Thailand
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Chiang Mai, 50200, Thailand
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Khon Kaen, 40002, Thailand
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Adana, 01060, Turkey (Türkiye)
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Ankara, 06230, Turkey (Türkiye)
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Kahramanmaraş, 46100, Turkey (Türkiye)
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Kayseri, 38039, Turkey (Türkiye)
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Odunpazari, 26080, Turkey (Türkiye)
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Corby, NN17 2UR, United Kingdom
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London, E1 1BB, United Kingdom
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London, W6 7HY, United Kingdom
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Prescot, L35 5DR, United Kingdom
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Swindon, SN3 6BB, United Kingdom
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Thetford, IP24 1JD, United Kingdom
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Weston-super-Mare, BS24 7PR, United Kingdom
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Yate, BS37 4AX, United Kingdom
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Hanoi, 100000, Vietnam
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Ho Chi Minh City, 700000, Vietnam
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Hochiminh City, 700000, Vietnam

Conditions

Explore the condition pages connected to this study.

RESISTANT HYPERTENSION