New pill could tame Hormone-Driven high blood pressure

NCT ID NCT07007793

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Sep 30, 2025 · Last updated May 05, 2026 · Updated 24 times

Summary

This study tests a new drug called baxdrostat in about 250 adults with primary aldosteronism, a condition where the adrenal glands make too much of a hormone, causing high blood pressure. The drug is taken daily and compared to a placebo to see if it lowers blood pressure and restores normal hormone levels over 8 weeks. Participants must be 18 or older and willing to pause certain blood pressure medications during the trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

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Los Angeles, California, 90048, United States
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San Francisco, California, 94110, United States
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Farmington, Connecticut, 06030, United States
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Chicago, Illinois, 60611, United States
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Springfield, Illinois, 62702, United States
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Baltimore, Maryland, 21287, United States
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Boston, Massachusetts, 02111, United States
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Boston, Massachusetts, 02115, United States
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Ann Arbor, Michigan, 48109, United States
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Rochester, Minnesota, 55902, United States
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Olive Branch, Mississippi, 38654, United States
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Kansas City, Missouri, 64151, United States
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New York, New York, 10065, United States
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Cleveland, Ohio, 44195, United States
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Columbus, Ohio, 43210, United States
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Portland, Oregon, 97239, United States
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Bethlehem, Pennsylvania, 18017, United States
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Philadelphia, Pennsylvania, 19104, United States
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Columbia, South Carolina, 29203, United States
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Brownsville, Texas, 78526, United States
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Dallas, Texas, 75390, United States
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Brisbane, 4102, Australia
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Clayton, 3168, Australia
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Perth, 6000, Australia
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Calgary, Alberta, T2T 5C7, Canada
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Ottawa, Ontario, K1H 7W9, Canada
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Toronto, Ontario, M4G 3E8, Canada
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Montreal, Quebec, H4J 1C5, Canada
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Beijing, 100034, China
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Beijing, 100044, China
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Beijing, 100191, China
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Changsha, 430033, China
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Chengdu, 610041, China
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Chengdu, 610500, China
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Chongqing, 400042, China
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Nanjing, 2100008, China
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Shanghai, 200025, China
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Tianjin, 300050, China
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Wuhan, 430030, China
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Wuhan, 430060, China
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Xianyang, 750004, China
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Amiens, 80054, France
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Bois-Guillaume, 76230, France
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Bordeaux, 33076, France
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Lille, 59037, France
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Marseille, 13005, France
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Paris, 75018, France
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Paris, 75908, France
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Berlin, 12203, Germany
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Düsseldorf, 40225, Germany
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Kaiserslautern, 67655, Germany
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München, 80336, Germany
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Reinfeld (Holstein), 23858, Germany
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Würzburg, 97080, Germany
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Belagavi, 590010, India
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Delhi, 110029, India
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Hyderabad, 500012, India
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Kolkata, 700020, India
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Mumbai, 400008, India
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Mumbai, 400012, India
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Bologna, 40138, Italy
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Brescia, 25123, Italy
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Florence, 50134, Italy
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Milan, 20149, Italy
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Milan, 20162, Italy
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Torino, 10126, Italy
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Kawasaki-shi, 216-8511, Japan
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Kodaira-shi, 187-8510, Japan
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Minatoku, 108-8329, Japan
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Ōta-ku, 143-8541, Japan
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Shinjuku-ku, 162-8666, Japan
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Yokohama, 230-8765, Japan
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Yufu-shi, 879-5593, Japan
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Barcelona, 08036, Spain
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Madrid, 28034, Spain
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Madrid, 28040, Spain
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Madrid, 28046, Spain
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Seville, 41013, Spain
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Kaohsiung City, 80756, Taiwan
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Taichung, 40705, Taiwan
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Taipei, 10002, Taiwan
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Taoyuan, 333, Taiwan
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Yunlin, 640, Taiwan
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Zhubei, 302, Taiwan
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Cambridge, CB2 0QQ, United Kingdom
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Cardiff, CF14 4XW, United Kingdom
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Dundee, DD1 9SY, United Kingdom
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London, EC1A 7BE, United Kingdom
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London, SE1 9RT, United Kingdom

Conditions

Explore the condition pages connected to this study.

PRIMARY HYPERALDOSTERONISM