New pill could tame Hormone-Driven high blood pressure

NCT ID NCT07007793

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This study tests a new drug called baxdrostat in about 250 adults with primary aldosteronism, a condition where the adrenal glands make too much aldosterone, causing high blood pressure. Participants take baxdrostat or a placebo daily for 8 weeks to see if it lowers blood pressure and restores normal hormone levels. The goal is to find a better treatment option for this specific form of high blood pressure.

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Conditions

The condition(s) this trial relates to.

hyperaldosteronism primary aldosteronism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PRIMARY HYPERALDOSTERONISM

Contacts and locations

Locations

Research Site
WITHDRAWN

Los Angeles, California, 90048, United States
Research Site
ACTIVE_NOT_RECRUITING

San Francisco, California, 94110, United States
Research Site
ACTIVE_NOT_RECRUITING

Farmington, Connecticut, 06030, United States
Research Site
RECRUITING

Chicago, Illinois, 60611, United States
Research Site
ACTIVE_NOT_RECRUITING

Springfield, Illinois, 62702, United States
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ACTIVE_NOT_RECRUITING

Baltimore, Maryland, 21287, United States
Research Site
ACTIVE_NOT_RECRUITING

Boston, Massachusetts, 02111, United States
Research Site
ACTIVE_NOT_RECRUITING

Boston, Massachusetts, 02115, United States
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ACTIVE_NOT_RECRUITING

Ann Arbor, Michigan, 48109, United States
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ACTIVE_NOT_RECRUITING

Rochester, Minnesota, 55902, United States
Research Site
RECRUITING

Olive Branch, Mississippi, 38654, United States
Research Site
WITHDRAWN

Kansas City, Missouri, 64151, United States
Research Site
WITHDRAWN

New York, New York, 10065, United States
Research Site
ACTIVE_NOT_RECRUITING

Cleveland, Ohio, 44195, United States
Research Site
ACTIVE_NOT_RECRUITING

Columbus, Ohio, 43210, United States
Research Site
WITHDRAWN

Portland, Oregon, 97239, United States
Research Site
ACTIVE_NOT_RECRUITING

Bethlehem, Pennsylvania, 18017, United States
Research Site
ACTIVE_NOT_RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Research Site
RECRUITING

Columbia, South Carolina, 29203, United States
Research Site
WITHDRAWN

Brownsville, Texas, 78526, United States
Research Site
ACTIVE_NOT_RECRUITING

Dallas, Texas, 75390, United States
Research Site
RECRUITING

Brisbane, 4102, Australia
Research Site
RECRUITING

Clayton, 3168, Australia
Research Site
RECRUITING

Perth, 6000, Australia
Research Site
RECRUITING

Calgary, Alberta, T2T 5C7, Canada
Research Site
RECRUITING

Ottawa, Ontario, K1H 7W9, Canada
Research Site
RECRUITING

Toronto, Ontario, M4G 3E8, Canada
Research Site
RECRUITING

Montreal, Quebec, H4J 1C5, Canada
Research Site
ACTIVE_NOT_RECRUITING

Beijing, 100034, China
Research Site
ACTIVE_NOT_RECRUITING

Beijing, 100044, China
Research Site
ACTIVE_NOT_RECRUITING

Beijing, 100191, China
Research Site
ACTIVE_NOT_RECRUITING

Changsha, 430033, China
Research Site
ACTIVE_NOT_RECRUITING

Chengdu, 610041, China
Research Site
WITHDRAWN

Chengdu, 610500, China
Research Site
ACTIVE_NOT_RECRUITING

Chongqing, 400042, China
Research Site
ACTIVE_NOT_RECRUITING

Nanjing, 2100008, China
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ACTIVE_NOT_RECRUITING

Shanghai, 200025, China
Research Site
ACTIVE_NOT_RECRUITING

Tianjin, 300050, China
Research Site
ACTIVE_NOT_RECRUITING

Wuhan, 430030, China
Research Site
COMPLETED

Wuhan, 430060, China
Research Site
RECRUITING

Xianyang, 750004, China
Research Site
ACTIVE_NOT_RECRUITING

Amiens, 80054, France
Research Site
ACTIVE_NOT_RECRUITING

Bois-Guillaume, 76230, France
Research Site
ACTIVE_NOT_RECRUITING

Bordeaux, 33076, France
Research Site
ACTIVE_NOT_RECRUITING

Lille, 59037, France
Research Site
WITHDRAWN

Marseille, 13005, France
Research Site
ACTIVE_NOT_RECRUITING

Paris, 75018, France
Research Site
ACTIVE_NOT_RECRUITING

Paris, 75908, France
Research Site
RECRUITING

Berlin, 12203, Germany
Research Site
RECRUITING

Düsseldorf, 40225, Germany
Research Site
RECRUITING

Kaiserslautern, 67655, Germany
Research Site
RECRUITING

München, 80336, Germany
Research Site
RECRUITING

Reinfeld (Holstein), 23858, Germany
Research Site
RECRUITING

Würzburg, 97080, Germany
Research Site
ACTIVE_NOT_RECRUITING

Belagavi, 590010, India
Research Site
ACTIVE_NOT_RECRUITING

Delhi, 110029, India
Research Site
ACTIVE_NOT_RECRUITING

Hyderabad, 500012, India
Research Site
ACTIVE_NOT_RECRUITING

Kolkata, 700020, India
Research Site
WITHDRAWN

Mumbai, 400008, India
Research Site
ACTIVE_NOT_RECRUITING

Mumbai, 400012, India
Research Site
ACTIVE_NOT_RECRUITING

Bologna, 40138, Italy
Research Site
ACTIVE_NOT_RECRUITING

Brescia, 25123, Italy
Research Site
ACTIVE_NOT_RECRUITING

Florence, 50134, Italy
Research Site
ACTIVE_NOT_RECRUITING

Milan, 20149, Italy
Research Site
ACTIVE_NOT_RECRUITING

Milan, 20162, Italy
Research Site
ACTIVE_NOT_RECRUITING

Torino, 10126, Italy
Research Site
ACTIVE_NOT_RECRUITING

Kawasaki-shi, 216-8511, Japan
Research Site
ACTIVE_NOT_RECRUITING

Kodaira-shi, 187-8510, Japan
Research Site
ACTIVE_NOT_RECRUITING

Minatoku, 108-8329, Japan
Research Site
ACTIVE_NOT_RECRUITING

Ōta-ku, 143-8541, Japan
Research Site
ACTIVE_NOT_RECRUITING

Shinjuku-ku, 162-8666, Japan
Research Site
ACTIVE_NOT_RECRUITING

Yokohama, 230-8765, Japan
Research Site
ACTIVE_NOT_RECRUITING

Yufu-shi, 879-5593, Japan
Research Site
ACTIVE_NOT_RECRUITING

Barcelona, 08036, Spain
Research Site
ACTIVE_NOT_RECRUITING

Madrid, 28034, Spain
Research Site
RECRUITING

Madrid, 28040, Spain
Research Site
ACTIVE_NOT_RECRUITING

Madrid, 28046, Spain
Research Site
RECRUITING

Seville, 41013, Spain
Research Site
WITHDRAWN

Kaohsiung City, 80756, Taiwan
Research Site
ACTIVE_NOT_RECRUITING

Taichung, 40705, Taiwan
Research Site
ACTIVE_NOT_RECRUITING

Taipei, 10002, Taiwan
Research Site
TERMINATED

Taoyuan, 333, Taiwan
Research Site
WITHDRAWN

Yunlin, 640, Taiwan
Research Site
ACTIVE_NOT_RECRUITING

Zhubei, 302, Taiwan
Research Site
ACTIVE_NOT_RECRUITING

Cambridge, CB2 0QQ, United Kingdom
Research Site
ACTIVE_NOT_RECRUITING

Cardiff, CF14 4XW, United Kingdom
Research Site
COMPLETED

Dundee, DD1 9SY, United Kingdom
Research Site
ACTIVE_NOT_RECRUITING

London, EC1A 7BE, United Kingdom
Research Site
ACTIVE_NOT_RECRUITING

London, SE1 9RT, United Kingdom

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