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Batoclimab shows promise for thyroid eye disease in extension study

NCT ID NCT05517447

Terminated Disease control Sponsor: Immunovant Sciences GmbH Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is for people who finished earlier trials of batoclimab for thyroid eye disease. It has two parts: one watches how long benefits last without treatment, and the other gives batoclimab to see if it helps more patients. The goal is to see if the drug can control eye bulging and other symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
batoclimab
What this could lead to
If successful, this could show that batoclimab helps control thyroid eye disease symptoms longer and in more patients.
What could go wrong
This trial was terminated early, so results may be limited. It's an extension study, meaning it builds on earlier work, and the drug may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

autoimmune disease endocrine exophthalmos Graves Ophthalmopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

THYROID EYE DISEASE

Contacts and locations

Locations

  • Site Number - 1501

    Aurora, Colorado, 80045, United States

  • Site Number - 1508

    Houston, Texas, 77030, United States

  • Site Number - 1511

    Morgantown, West Virginia, 26506, United States

  • Site Number - 1513

    Rochester, Minnesota, 55905, United States

  • Site Number - 1518

    Milwaukee, Wisconsin, 53226, United States

  • Site Number - 1520

    Glendora, California, 91741, United States

  • Site Number - 1526

    Livonia, Michigan, 48152, United States

  • Site Number - 1540

    Las Vegas, Nevada, 89184, United States

  • Site Number - 1558

    Mesquite, Texas, 75149, United States

  • Site Number - 1990

    San Juan, 00921, Puerto Rico

  • Site Number - 3101

    Krakow, 30-688, Poland

  • Site Number - 3104

    Lublin, 20-171, Poland

  • Site Number - 3105

    Lublin, 60-354, Poland

  • Site Number - 3107

    Gliwice, Silesian Voivodeship, 44-102, Poland

  • Site Number - 3450

    Tbilisi, 159, Georgia

  • Site Number - 3451

    Tbilisi, 159, Georgia

  • Site Number - 3454

    Tbilisi, 114, Georgia

  • Site Number - 3455

    Tbilisi, 114, Georgia

  • Site Number - 3600

    Santiago de Compostela, 15706, Spain

  • Site Number - 3602

    Barcelona, Catalonia, 8006, Spain

  • Site Number - 3603

    Valencia, 46026, Spain

  • Site Number - 3604

    Madrid, 28034, Spain

  • Site Number - 3606

    Seville, 41009, Spain

  • Site Number - 4670

    Ghent, B-9000, Belgium

  • Site Number - 4671

    Bruges, 8000, Belgium

  • Site Number - 4672

    Brussels, 1070, Belgium

  • Site Number - 4673

    Brussels, 1200, Belgium

  • Site Number - 4760

    Ramat Gan, Tel Aviv, 5265601, Israel

  • Site Number - 4761

    Jerusalem, 91120, Israel

  • Site Number - 4762

    Petah Tikva, 4941492, Israel

  • Site Number - 4764

    Afula, 1834111, Israel

  • Site Number - 6201

    Pisa, 56124, Italy

  • Site Number - 6202

    Rome, 00189, Italy

  • Site Number - 6203

    Milan, 20149, Italy

  • Site Number - 6204

    Milan, 20122, Italy

  • Site Number - 6205

    Naples, 80131, Italy

  • Site Number - 6207

    Catania, CAP95125, Italy

  • Site Number - 6209

    Palermo, 90127, Italy

  • Site Number - 7300

    Manchester, M139WL, United Kingdom

  • Site Number - 7302

    Newcastle upon Tyne, NE1 3BZ, United Kingdom

  • Site Number - 7303

    London, EC1V 2PD, United Kingdom

  • Site Number - 7305

    Guildford, GU2 7XX, United Kingdom

  • Site Number - 7308

    Sheffield, S102SB, United Kingdom

  • Site Number - 7312

    London, W1T 6AH, United Kingdom

  • Site Number - 7313

    London, W1T 7HA, United Kingdom

  • Site Number - 7550

    Budapest, 1133, Hungary

  • Site Number - 7552

    Pécs, 7623, Hungary

  • Site Number - 7565

    Sydney, 2000, Australia

  • Site Number - 7570

    Christchurch, 8013, New Zealand

  • Site Number - 9200

    Bratislava, 82606, Slovakia

  • Site Number - 9201

    Bratislava, Slovakia

  • Site Number - 9202

    Trenčín, 91101, Slovakia

  • Site Number - 9300

    Riga, LV-1006, Latvia

  • Site Number - 9301

    Ogre, LV-5001, Latvia

  • Site Number - 9302

    Ventspils, LV3601, Latvia

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