Dietary intervention aims to tame weight regain in Graves' patients

NCT ID NCT06921304

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a personalized low-calorie Mediterranean-style diet, combined with lifestyle coaching, can prevent people newly diagnosed with Graves' disease from regaining too much weight after their thyroid levels normalize. Fifty-four adults will be randomly assigned to either the diet program or standard care, and followed for a year. The goal is to see if the diet helps maintain a healthy weight and improves body composition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Intensive Lifestyle Intervention (personalized low-energy Mediterranean-style diet and lifestyle counseling)

What this could lead to

If it works, this could show that structured dietary support helps people with Graves' disease avoid unhealthy weight gain while on standard medication.

What could go wrong

This is a small early-stage trial (54 people) testing a behavioral change, not a drug. Results may not apply to everyone, and sticking to the diet long-term can be challenging.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Body Weight Graves disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Istituti Clinici Maugeri IRCCS

    Pavia, PV, 27100, Italy