Dietary intervention aims to tame weight regain in Graves' patients

NCT ID NCT06921304

Ongoing Disease control Sponsor: Istituti Clinici Scientifici Maugeri SpA Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a personalized low-calorie Mediterranean-style diet, combined with lifestyle coaching, can prevent people newly diagnosed with Graves' disease from regaining too much weight after their thyroid levels normalize. Fifty-four adults will be randomly assigned to either the diet program or standard care, and followed for a year. The goal is to see if the diet helps maintain a healthy weight and improves body composition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Intensive Lifestyle Intervention (personalized low-energy Mediterranean-style diet and lifestyle counseling)
What this could lead to: If it works, this could show that structured dietary support helps people with Graves' disease avoid unhealthy weight gain while on standard medication.
What could go wrong: This is a small early-stage trial (54 people) testing a behavioral change, not a drug. Results may not apply to everyone, and sticking to the diet long-term can be challenging.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for GRAVES DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Body Weight Graves disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GRAVES DISEASE

Contacts and locations

Locations

Istituti Clinici Maugeri IRCCS

Pavia, PV, 27100, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.