New pill could help seniors ditch steroids for painful muscle disease

NCT ID NCT07279688

First seen Jan 11, 2026 · Last updated Jun 15, 2026 · Updated 24 times

Summary

This study tests whether adding baricitinib (a JAK inhibitor pill) to standard steroid treatment helps people with polymyalgia rheumatica (PMR) achieve disease control without needing long-term steroids. About 140 adults aged 50+ with active PMR will receive baricitinib (2 mg or 4 mg) or a placebo for 6 months, alongside a steroid taper. The goal is to see if more patients can stop steroids and keep their disease quiet at 24 weeks.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for POLYMYALGIA RHEUMATICA (PMR) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • APHP - Kremlin-Bicêtre

    NOT_YET_RECRUITING

    Le Kremlin-Bicêtre, 94270, France

    Contact Email: •••••@•••••

  • Besançon-CIC

    RECRUITING

    Besançon, 25000, France

    Contact Email: •••••@•••••

  • CARVAJAL ALEGRIA Guillermo

    RECRUITING

    Tours, France

    Contact Email: •••••@•••••

  • CHU Reims

    NOT_YET_RECRUITING

    Reims, France

    Contact Email: •••••@•••••

  • CHU de Bordeaux Pellegrin

    NOT_YET_RECRUITING

    Bordeaux, 33076, France

    Contact Email: •••••@•••••

  • CHU de Nice

    RECRUITING

    Nice, 06000, France

    Contact Email: •••••@•••••

  • CHU de Toulouse

    NOT_YET_RECRUITING

    Toulouse, 31059, France

    Contact Email: •••••@•••••

  • DIREZ Guillaume

    RECRUITING

    Le Mans, France

    Contact Email: •••••@•••••

  • Dr Alain SARAUX

    RECRUITING

    Brest, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • FAUTREL Bruno - AP-HP La Pitié-Salpétrière

    NOT_YET_RECRUITING

    Paris, France

    Contact Email: •••••@•••••

  • FLIPO René-Marc

    NOT_YET_RECRUITING

    Lille, France

    Contact Email: •••••@•••••

  • GOTTENBERG Jacques-Eric

    RECRUITING

    Strasbourg, France

    Contact Email: •••••@•••••

  • LE HENAFF Catherine

    RECRUITING

    Morlaix, France

    Contact Email: •••••@•••••

  • LEGRAND Jean-Louis

    NOT_YET_RECRUITING

    Arras, France

    Contact Email: •••••@•••••

  • LESKE Charles

    RECRUITING

    Cholet, France

    Contact Email: •••••@•••••

  • OTTAVIANI Sébastien - AP-HP Bichat

    NOT_YET_RECRUITING

    Paris, France

    Contact Email: •••••@•••••

  • PRATI Clément

    RECRUITING

    Besançon, France

    Contact Email: •••••@•••••

  • RAMON André

    NOT_YET_RECRUITING

    Dijon, France

    Contact Email: •••••@•••••

  • RAT Anne-Christine

    RECRUITING

    Caen, France

    Contact Email: •••••@•••••

  • TOURNADRE Anne

    NOT_YET_RECRUITING

    Clermont-Ferrand, France

    Contact Email: •••••@•••••

  • VIDAL François

    RECRUITING

    Aix-en-Provence, France

    Contact Email: •••••@•••••

  • WIRTH Théo

    RECRUITING

    Marseille, France

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.