Blood test may detect hidden giant cell arteritis in PMR patients
NCT ID NCT06609668
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This pilot study is testing whether measuring a protein called thrombomodulin in the blood can help rule out giant cell arteritis (GCA) in people with polymyalgia rheumatica (PMR). GCA is a serious inflammation of the arteries that can cause blindness or stroke if not treated. The study will enroll 78 adults over 50 with PMR, take blood samples before treatment, and check thrombomodulin levels. If the test works, it could reduce the need for expensive or invasive tests like ultrasound or biopsy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- thrombomodulin blood test
- What this could lead to
- If successful, this blood test could help doctors quickly identify which PMR patients need further testing for GCA, potentially preventing blindness or stroke.
- What could go wrong
- This is a small pilot study (78 people) testing a single biomarker. The test may not be accurate enough to replace current imaging or biopsy, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU Dijon Bourgogne
RECRUITINGDijon, 21000, France
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