New hope for kids with rare arthritis: drug trial launches
NCT ID NCT04088396
First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 15 times
Summary
This study tests whether baricitinib is safe and effective for children aged 1 to 18 with systemic juvenile idiopathic arthritis (sJIA), a condition that causes joint swelling and fever. About 58 children will receive either baricitinib or an existing drug called tocilizumab. The goal is to see if baricitinib can reduce arthritis symptoms and control the disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Locations
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9 Eylul University Hospital
RECRUITINGIzmir, 35340, Turkey (Türkiye)
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Alder Hey Children's Hospital
RECRUITINGLiverpool, L12 2AB, United Kingdom
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Azienda Ospedaliera Spedali Civili di Brescia
RECRUITINGBrescia, 25123, Italy
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Azienda Sanitaria Locale n. 2 - Lanciano Vasto Chieti
COMPLETEDChieti, 66100, Italy
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Azienda di Rilievo Nazionale e Alta Specializzazione Civico Di Cristina Benfratelli
RECRUITINGPalermo, 90127, Italy
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Bristol Royal Hospital for Children
RECRUITINGBristol, BS2 8BJ, United Kingdom
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Centralny Szpital Kliniczny Uniwersytetu Medycznego w Lodzi
RECRUITINGLodz, 91-738, Poland
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Centre Hospitalier Universitaire de Nîmes - Hôpital Universitaire Carémeau
RECRUITINGNîmes, 30029, France
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Centre Hospitalier Universitaire de Poitiers
RECRUITINGPoitiers, 86021, France
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Centro Medico Privado de Reumatologia
RECRUITINGSAN M. de Tucuman, T4000AXL, Argentina
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Centro Specialistico Ortopedico Traumatologico Gaetano Pini - CTO
RECRUITINGMilan, 20122, Italy
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Chiba Children's Hospital
RECRUITINGChiba, 266-0007, Japan
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Clinstile, S.A. de C.V.
RECRUITINGMéxico, 06700, Mexico
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Crea de Guadalajara
RECRUITINGGuadalajara, 44600, Mexico
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Detska nemocnice FN Brno
RECRUITINGBrno, 613 00, Czechia
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Faculdade de Medicina da UNESP
RECRUITINGBotucatu, 18618-686, Brazil
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Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
COMPLETEDMilan, 20122, Italy
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Great Ormond Street Hospital For Children NHS Foundation Trust
COMPLETEDLondon, WC1N 3JH, United Kingdom
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Hospices Civils de Lyon - Hôpital Femme Mère Enfant
RECRUITINGBron, 69500, France
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Hospital Infantil Universitario Niño Jesús
RECRUITINGMadrid, 28009, Spain
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Hospital Sant Joan de Déu
RECRUITINGEsplugues de Llobregat, 08950, Spain
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Hospital Universitari i Politecnic La Fe
RECRUITINGValencia, 46026, Spain
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Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León
RECRUITINGMonterrey, 66460, Mexico
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Hospital Universitario La Paz
RECRUITINGMadrid, 28046, Spain
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Hospital Universitario Ramón y Cajal
RECRUITINGMadrid, 28034, Spain
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Hospital Universitario Virgen Del Rocio
RECRUITINGSeville, 41013, Spain
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Hospital de Clinicas de Porto Alegre
RECRUITINGPorto Alegre, 90035-903, Brazil
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Hôpital Universitaire Necker Enfants Malades
RECRUITINGParis, 75015, France
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Hôpitaux Universitaires Paris Sud - Hôpital Bicêtre
RECRUITINGLe Kremlin-Bicêtre, 94270, France
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IPITEC
NOT_YET_RECRUITINGSão Paulo, 01221-020, Brazil
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IRCCS Istituto Giannina Gaslini
RECRUITINGGenova, 16147, Italy
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Institute of Science Tokyo Hospital
RECRUITINGBunkyō, 113-8510, Japan
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Instituto CAICI SRL
RECRUITINGRosario, S2000, Argentina
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Instituto da Crianca do Hospital das Clinicas da FMUSP
RECRUITINGSão Paulo, 05403-000, Brazil
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Instituto de Investigaciones Clínicas para la Salud
RECRUITINGDurango, 34000, Mexico
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Investigacion y Biomedicina de Chihuahua
RECRUITINGChihuahua City, 31000, Mexico
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Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine
RECRUITINGIstanbul, 34098, Turkey (Türkiye)
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Kagoshima University Hospital
RECRUITINGKagoshima, 890-8520, Japan
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Kanagawa Children's Medical Center
RECRUITINGYokohama, 232-8555, Japan
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Meir Medical Center
RECRUITINGKfar Saba, 4428164, Israel
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Miyagi Children's Hospital
RECRUITINGSendai, 989-3126, Japan
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Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji
RECRUITINGWarsaw, 02-637, Poland
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Osaka Medical and Pharmaceutical University Hospital
RECRUITINGTakatsuki, 569-8686, Japan
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Ospedale Infantile Burlo Garofolo
RECRUITINGTrieste, 34137, Italy
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Oxford University Hospitals - Nuffield Orthopaedic Centre
RECRUITINGOxford, OX3 7HE, United Kingdom
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Schneider Children's Medical Center
RECRUITINGPetah Tikva, 49202, Israel
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Sheba Medical Center
RECRUITINGRamat Gan, 5262100, Israel
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Sheffield Children's Hospital
RECRUITINGSheffield, S10 2TH, United Kingdom
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Sir Ganga Ram Hospital
RECRUITINGNew Delhi, 110060, India
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UZ Gent
RECRUITINGGhent, 9000, Belgium
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Universidade Federal de Sao Paulo
RECRUITINGSão Paulo, 04024-001, Brazil
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University of Naples Federico II
RECRUITINGNaples, 80131, Italy
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Vseobecna fakultni nemocnice v Praze
RECRUITINGPrague, 12808, Czechia
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Wojewódzki Specjalistyczny Szpital Dziecięcy im. św. Ludwika w Krakowie
RECRUITINGKrakow, 31-503, Poland
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Yokohama City University Hospital
RECRUITINGYokohama, 236-0004, Japan
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Conditions
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