Balloon battle: which coated catheter wins for tiny heart arteries?

NCT ID NCT04058990

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tests two types of drug-coated balloon catheters to treat small, newly blocked heart arteries. About 180 adults with stable or unstable angina will be randomly assigned to receive one of the two devices during a standard angioplasty procedure. The goal is to see which balloon better keeps the artery open and reduces the chance of future heart problems.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Paclitaxel-coated balloon catheter

What this could lead to

If successful, this could provide a better treatment option for people with small vessel coronary artery disease, potentially reducing the need for stents or repeat procedures.

What could go wrong

This is a relatively small trial (180 participants) and compares two existing devices, so major breakthroughs are unlikely. There is a risk of heart attack or need for repeat procedures, as with any angioplasty.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Japan Labour Health and Welfare Organization Kanto Rosai Hospital

    Kawasaki, Kanagawa, 211-8510, Japan

  • Kokura Memorial Hospital

    Kitakyushu, Fukuoka, 802-8555, Japan

  • Kyoto-Katsura Hospital

    Kyoto, Kyoto, 615-8256, Japan

  • Miyazaki Medical Association Hospital

    Miyazaki, Miyazaki, 880-0834, Japan

  • Osaka Saiseikai Nakatsu Hospital

    Kita, Osaka, 530-0012, Japan

  • Saiseikai Yokohama-City Eastern Hospital

    Yokohama, Kanagawa, 230-8765, Japan

  • Sakurabashi Watanabe Advanced Healthcare Hospital

    Osaka, Osaka, 530-0001, Japan

  • Sapporo Higashi Tokushukai Hospital

    Sapporo, Hokkaido, 065-0033, Japan

  • Sendai Kousei Hospital

    Sendai, Miyagi, 980-0873, Japan

  • Shonan Kamakura General Hospital

    Ōfuna, Kanagawa, 247-8533, Japan

  • Showa Medical University Hospital

    Shinagawa-Ku, Tokyo, 142-8666, Japan

  • Teikyo University Hospital

    tabashi City, Tokyo, 173-8606, Japan

  • Toho University Ohashi Medical Center

    Meguro City, Tokyo, 153-8515, Japan

  • Tokyo Women's Medical University Hospital

    Shinjuku-Ku, Tokyo, 162-8666, Japan