Can a muscle relaxant curb alcoholism? new trial results are in
NCT ID NCT01604330
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tested whether the drug baclofen, typically used for muscle spasms, can help people with alcoholism reduce their drinking. Over 300 adults who wanted to cut back or quit took either baclofen or a placebo for a year. The main goal was to see if more people on baclofen achieved low-risk drinking or abstinence according to WHO guidelines.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Baclofen (a muscle relaxant drug)
What this could lead to
If it works, this could offer a new medication option to help people with alcoholism drink less or stay abstinent.
What could go wrong
This is a completed Phase 2/3 trial, but results may not apply to everyone. Baclofen can cause side effects like drowsiness and muscle weakness, and the optimal dose is still unclear.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Paris Descartes University
Paris, 75014, France