Can a muscle relaxant curb alcoholism? new trial results are in
NCT ID NCT01604330
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tested whether the drug baclofen, typically used for muscle spasms, can help people with alcoholism reduce their drinking. Over 300 adults who wanted to cut back or quit took either baclofen or a placebo for a year. The main goal was to see if more people on baclofen achieved low-risk drinking or abstinence according to WHO guidelines.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Baclofen (a muscle relaxant drug)
- What this could lead to
- If it works, this could offer a new medication option to help people with alcoholism drink less or stay abstinent.
- What could go wrong
- This is a completed Phase 2/3 trial, but results may not apply to everyone. Baclofen can cause side effects like drowsiness and muscle weakness, and the optimal dose is still unclear.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Paris Descartes University
Paris, 75014, France
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Other studies related to the condition(s) this trial covers.
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