Pacemaker tweak may quietly lower blood pressure without extra pills

NCT ID NCT05086523

Completed Disease control Sponsor: BackBeat Medical Inc Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests a special pacemaker called the BackBeat Moderato that can adjust its pacing to help control high blood pressure. Researchers will turn the device on and off for short periods in 28 people who already have the pacemaker implanted, measuring how their blood pressure changes. The goal is to see if the device can safely lower systolic blood pressure when active.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: BackBeat Moderato device (programmable hypertension control via pacemaker)
What this could lead to: If it works, this could offer a new way to manage high blood pressure using a pacemaker, potentially reducing the need for daily pills.
What could go wrong: This is a small, early-phase study with only 28 participants, so results may not apply to everyone. The device requires implantation, which carries surgical risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

essential hypertension essential hypertension, genetic hypertensive disorder Isolated Systolic Hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERTENSION,ESSENTIAL SYSTOLIC HYPERTENSION

Contacts and locations

Locations

Na Homolce Hospital

Prague, 15030, Czechia
Pomeranian Medical University Hospital no. 2

Szczecin, 70-111, Poland
Samodzielnym Publicznym Centralnym Szpitalem Klinicznym

Warsaw, 02-097, Poland
Semmelweis University Heart and Vascular Center

Budapest, 1122, Hungary
Silesian Center for Heart Diseases

Zabrze, 41-800, Poland
Szpital Kliniczny Przemiemienia Panskiego

Poznan, 61-848, Poland

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