Gut feeling: can a probiotic soothe anxiety and depression?
NCT ID NCT07187492
First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 33 times
Summary
This study tests whether a probiotic called Bacillus coagulans can help reduce anxiety and depression in people with functional dyspepsia, a common stomach disorder. 180 adults will receive either the probiotic or a placebo for 4 weeks, alongside standard stomach treatments. The main goal is to see if their mood improves, measured by a standard questionnaire.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Air Force Medical University
RECRUITINGXi’an, Shanxi, China
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Bacillus coagulans (a probiotic)
What this could lead to
If it works, this could point toward a simple probiotic supplement to help manage anxiety and depression in people with functional dyspepsia.
What could go wrong
This is a small, early-phase trial with only 180 participants. The effect may be small or no better than placebo, and results may not apply to everyone with anxiety or depression.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.