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Simple antibiotic pill may protect mothers and babies during induced labor

NCT ID NCT06543290

Recruiting now Disease control Sponsor: Arrowhead Regional Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether giving a single 2-gram dose of azithromycin before starting labor induction can lower the risk of infections in both the mother and newborn. Researchers plan to enroll 400 pregnant women in their third trimester who are scheduled for labor induction. Half will receive the antibiotic and half a placebo, and the rates of infections like chorioamnionitis will be compared.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
azithromycin
What this could lead to
If it works, this could provide a simple, low-cost way to prevent serious infections during childbirth.
What could go wrong
This is an early Phase 1 trial, so the results are uncertain. The drug may not reduce infections as hoped, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Infections infectious disease chorioamnionitis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFECTIONS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Arrowhead Regional Medical Center

    RECRUITING

    Colton, California, 92324, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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