Common antibiotic may speed remission in kids with kidney disease

NCT ID NCT07320612

Completed Disease control Sponsor: University of Child Health Sciences and Children's Hospital, Lahore Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding the antibiotic azithromycin to standard steroid treatment helps children with steroid-sensitive nephrotic syndrome achieve remission faster. 160 children aged 2 to 14 were split into two groups: one received azithromycin plus steroids, the other only steroids. The goal was to see if the combination led to earlier remission and fewer relapses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: azithromycin
What this could lead to: If it works, this could point toward a way to help children with nephrotic syndrome reach remission faster and have fewer relapses.
What could go wrong: This is an early phase 1 trial, so results are preliminary. The addition of azithromycin may not improve outcomes and could cause side effects like heart rhythm issues or infections.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NEPHROTIC SYNDROME are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

nephrotic syndrome nephrotic syndrome of childhood - steroid sensitive

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEPHROTIC SYNDROME

Contacts and locations

Locations

UCHS

Lahore, Punjab Province, 54600, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.