New arthritis drug candidate AZD6912 begins first human safety tests

NCT ID NCT06115967

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tested a single dose of the experimental drug AZD6912 in 40 healthy adults to see if it is safe and how the body processes it. The study is a first step toward possibly treating rheumatoid arthritis, but it does not involve people with the disease. Results will help decide whether to test the drug in patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AZD6912

What this could lead to

If this drug is safe, it could lead to a new treatment option for rheumatoid arthritis.

What could go wrong

This is a very early Phase 1 trial in only 40 healthy people, not patients. It only tests safety and dosing, not whether the drug works for arthritis.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    Montreal, Quebec, H3P 3P1, Canada

  • Research Site

    Harrow, HA1 3UJ, United Kingdom