New immune drug AZD6750 targets Hard-to-Treat cancers

NCT ID NCT07115043

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 08, 2026 · Updated 2 times

Summary

This study tests a new drug, AZD6750, that helps the immune system fight cancer. It is for adults with advanced solid tumors like melanoma, lung, or breast cancer that have not responded to other treatments. The goal is to find the safest dose and see if it shrinks tumors when used alone or with other cancer drugs.

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Conditions

The condition(s) this trial relates to.

cutaneous neuroendocrine carcinoma gastric cancer gastric neoplasm gastroesophageal cancer gastroesophageal junction adenocarcinoma head and neck squamous cell carcinoma melanoma non-small cell lung carcinoma ovarian serous adenocarcinoma renal cell carcinoma skin squamous cell carcinoma squamous cell carcinoma Squamous Cell Carcinoma of Head and Neck triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GASTRIC CANCER/GASTROESOPHAGEAL JUNCTION CANCER HEAD AND NECK SQUAMOUS CELL CARCINOMA HIGH GRADE SEROUS OVARIAN CARCINOMA MELANOMA MERKEL CELL CARCINOMA NON-SMALL CELL LUNG CANCER RENAL CELL CARCINOMA SQUAMOUS CELL CARCINOMA (SKIN) TRIPLE NEGATIVE BREAST CANCER

Contacts and locations

Locations

Research Site
RECRUITING

Grand Rapids, Michigan, 49546, United States
Research Site
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St Louis, Missouri, 63110, United States
Research Site
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Pittsburgh, Pennsylvania, 15232, United States
Research Site
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Houston, Texas, 77030, United States
Research Site
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San Antonio, Texas, 78229, United States
Research Site
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Fairfax, Virginia, 22031, United States
Research Site
RECRUITING

East Melbourne, 3002, Australia
Research Site
RECRUITING

Chūōku, 104-0045, Japan
Research Site
RECRUITING

Kashiwa, 227-8577, Japan
Research Site
RECRUITING

Seoul, 03080, South Korea
Research Site
RECRUITING

Seoul, 06351, South Korea
Research Site
NOT_YET_RECRUITING

Seoul, 3722, South Korea
Research Site
NOT_YET_RECRUITING

Seoul, 5505, South Korea

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