New cancer pill tested in patients with no other options

NCT ID NCT00463814

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage study tested the safety of an experimental cancer drug called AZD6244, given as a capsule, in 58 adults with advanced solid tumors that had stopped responding to standard treatments. The main goal was to check for side effects and how the drug moves through the body. This is a Phase 1 trial, so it focuses on safety and dosing, not on curing the cancer.

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Conditions

The condition(s) this trial relates to.

cancer neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    Aurora, Colorado, 80045, United States

  • Research Site

    Nijmegen, 6525 GA, Netherlands

  • Research Site

    Utrecht, 3584 CX, Netherlands

  • Research Site

    Sutton, SM2 5PT, United Kingdom