New Heart-Kidney combo drug tested in tiny study

NCT ID NCT06639087

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This early study tested a new drug called AZD5462 added to the standard medicine dapagliflozin in people with heart failure and moderate kidney disease. Only 8 participants were enrolled before the study was stopped. The goal was to see if the combination is safe and affects how the body handles salt and kidney function.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
AZD5462
What this could lead to
If it works, this could point toward a new combination treatment to help people with both heart failure and kidney disease.
What could go wrong
This is a very early, tiny study (only 8 people) that was terminated, so results are limited. It may not lead to any new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    Sofia, 1612, Bulgaria

More trials for these conditions

Other studies related to the condition(s) this trial covers.