New drug AZD4954 enters first human tests for cholesterol and lp(a) conditions

NCT ID NCT06980428

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 25 times

Summary

This early-stage study tests the safety and tolerability of a new drug called AZD4954 in healthy volunteers and people with high Lp(a) or dyslipidemia (abnormal cholesterol levels). About 136 participants will receive either the drug or a placebo to see how the body processes it and if any side effects occur. This is a Phase 1 trial, so it focuses on safety and dosing, not on treating the condition.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    RECRUITING

    Glendale, California, 91206, United States

  • Research Site

    RECRUITING

    Inverness, Florida, 34452, United States

  • Research Site

    RECRUITING

    Jacksonville, Florida, 32216, United States

  • Research Site

    NOT_YET_RECRUITING

    Port Orange, Florida, 32127, United States

  • Research Site

    RECRUITING

    Brooklyn, Maryland, 21225, United States

  • Research Site

    RECRUITING

    San Antonio, Texas, 78229, United States

Conditions

Explore the condition pages connected to this study.