New drug targets inflammation in heart and kidney patients

NCT ID NCT06675175

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 29 times

Summary

This early-stage study tested a new drug called AZD4144 in 29 adults with both heart disease and chronic kidney disease. The goal was to check if the drug is safe and if it lowers certain markers of inflammation in the blood. Participants took either the drug or a placebo for 4 weeks, and researchers monitored side effects and changes in inflammatory proteins like IL-6.

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Contacts and locations

Locations

  • Research Site

    Glendale, California, 91203, United States

  • Research Site

    Daytona Beach, Florida, 32117, United States

  • Research Site

    Jacksonville, Florida, 32216, United States

  • Research Site

    Miami, Florida, 33125, United States

  • Research Site

    Port Orange, Florida, 32127, United States

  • Research Site

    Tampa, Florida, 33603, United States

  • Research Site

    Farmington Hills, Michigan, 48334, United States

  • Research Site

    The Bronx, New York, 10455, United States

  • Research Site

    Sherman, Texas, 75092, United States

  • Research Site

    Pleven, 5800, Bulgaria

  • Research Site

    Sofia, 1527, Bulgaria

  • Research Site

    Gyöngyös, 3200, Hungary

  • Research Site

    Kistarcsa, 2143, Hungary

  • Research Site

    Bucharest, 11658, Romania

  • Research Site

    Cluj-Napoca, 400006, Romania

Conditions

Explore the condition pages connected to this study.