New drug AZD1163 aims to ease rheumatoid arthritis pain

NCT ID NCT07276581

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests an experimental drug called AZD1163 in 320 people with moderate-to-severe rheumatoid arthritis who haven't gotten enough relief from standard treatments. Participants receive either AZD1163 or a placebo as an injection, along with their usual care. The main goal is to see if AZD1163 reduces joint swelling and tenderness after 12 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AZD1163 (an experimental drug given as an injection under the skin)

What this could lead to

If it works, this could lead to a new treatment option for people with rheumatoid arthritis who haven't responded well to standard therapies.

What could go wrong

This is an early Phase 2 trial with only 320 participants, so results may not apply to everyone. The drug may not work better than placebo, and side effects are still being studied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RHEUMATOID ARTHRITIS

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

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NOT_YET_RECRUITING

Glendale, Arizona, 85306, United States
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Prescott Valley, Arizona, 86314, United States
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Tucson, Arizona, 85748, United States
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La Jolla, California, 92037, United States
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San Dimas, California, 91773, United States
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San Leandro, California, 94578, United States
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Aurora, Colorado, 80045, United States
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Boynton Beach, Florida, 33435, United States
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Jacksonville, Florida, 32216, United States
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SUSPENDED

South Miami, Florida, 33143, United States
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Tampa, Florida, 33607, United States
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Winter Haven, Florida, 33880, United States
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Marietta, Georgia, 30060, United States
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Skokie, Illinois, 60076, United States
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Willowbrook, Illinois, 60527, United States
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Lake Charles, Louisiana, 70605, United States
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Baltimore, Maryland, 21224, United States
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New Bedford, Massachusetts, 02740, United States
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Kansas City, Missouri, 64151, United States
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St Louis, Missouri, 63131, United States
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Henderson, Nevada, 89052, United States
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Myrtle Beach, South Carolina, 29572, United States
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Austin, Texas, 78745, United States
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Baytown, Texas, 77521, United States
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Houston, Texas, 77027, United States
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Houston, Texas, 77089, United States
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Mesquite, Texas, 75150, United States
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Tomball, Texas, 77375, United States
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Caba, C1128AAF, Argentina
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Ciudad de Buenos Aires, C1015ABO, Argentina
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Ciudad de Buenos Aires, C1428DUQ, Argentina
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Córdoba, X5000EDC, Argentina
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San Isidro, 1643, Argentina
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San Miguel de Tucumán, T4000AXL, Argentina
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Juiz de Fora, 36010 570, Brazil
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Pelotas, 96040-010, Brazil
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Porto Alegre, 90035-903, Brazil
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Porto Alegre, 9061-000, Brazil
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Salvador, 41820-020, Brazil
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São Paulo, 04266-010, Brazil
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NOT_YET_RECRUITING

São Paulo, 05403-9000, Brazil
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Haskovo, 6304, Bulgaria
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Pleven, 5800, Bulgaria
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Sofia, 1113, Bulgaria
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Sofia, 1336, Bulgaria
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Sofia, 1606, Bulgaria
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Sofia, 1612, Bulgaria
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Windsor, Ontario, N8X 5A7, Canada
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Trois-Rivières, Quebec, G9A 3Y2, Canada
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Providencia, 7510186, Chile
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Santiago, 7500571, Chile
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Santiago, 7500587, Chile
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Temuco, 4810345, Chile
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Valdivia, 5110683, Chile
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Victoria, 4720097, Chile
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Viña del Mar, 2531172, Chile
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Beijing, 100144, China
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Beijing, 100730, China
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Changchun, 130021, China
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Changsha, 410008, China
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Guangzhou, 510515, China
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Jiujiang, 332000, China
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Kunming, 650032, China
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Linyi, CN-276003, China
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Nanchong, 637000, China
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Panjin, 124000, China
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Pingxiang, 337055, China
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Shantou, 515041, China
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Xuzhou, 221009, China
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Yangzhou, 225001, China
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Zhengzhou, 450000, China
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Bad Doberan, 18209, Germany
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Berlin, 10777, Germany
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Hamburg, 20095, Germany
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Sendenhorst, 48324, Germany
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Budapest, 1023, Hungary
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Budapest, 1027, Hungary
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Budapest, 1036, Hungary
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Debrecen, 4032, Hungary
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Gyula, 5700, Hungary
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Szeged, 6725, Hungary
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Székesfehérvár, 8000, Hungary
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Veszprém, 8200, Hungary
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Aomori, 030-8553, Japan
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Bunkyō City, 113-8655, Japan
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Fukuoka, 815-8555, Japan
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Hamamatsu, 430-0906, Japan
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Hitachi-Naka, 312-0057, Japan
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Iizuka-shi, 820-8505, Japan
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Kawachinagano-shi, 586-8521, Japan
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Matsuyama, 790-8524, Japan
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Meguro-ku, 152-8902, Japan
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Miyazaki, 880-0834, Japan
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Nagoya, 457-8511, Japan
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Okayama, 700-8557, Japan
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Sagamihara-shi, 252-0315, Japan
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Sapporo, 060-0001, Japan
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Sasebo-shi, 857-1195, Japan
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Sayama-shi, 350-1305, Japan
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Yokohama, 236-0037, Japan
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Chihuahua City, 31000, Mexico
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Estado de México, 50090, Mexico
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Guadalajara, 44160, Mexico
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Guadalajara, 44650, Mexico
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Guadalajara, 44690, Mexico
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Gustavo A. Madero, 07300, Mexico
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Mexicali, 021100, Mexico
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Mexico City, 06700, Mexico
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Mérida, 97070, Mexico
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Monterrey, 64460, Mexico
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San Luis Potosí City, 78213, Mexico
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Krakow, 30-002, Poland
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Krakow, 30-727, Poland
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Torun, 87-100, Poland
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Warsaw, 00-874, Poland
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Wroclaw, 50-244, Poland
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Caguas, 00725, Puerto Rico
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Brackenfell, 7560, South Africa
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Cape Town, 7500, South Africa
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Durban, 4319, South Africa
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Pinelands, 7405, South Africa
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Pretoria, 0002, South Africa
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Pretoria, South Africa
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Somerset West, 7130, South Africa
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Barcelona, 08003, Spain
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Barcelona, 08035, Spain
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Barcelona, 08041, Spain
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Málaga, 29009, Spain
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Sabadell, 08208, Spain
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Santiago de Compostela, 15706, Spain
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Valencia, 46026, Spain
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Ivano-Frankivsk, 76018, Ukraine
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Kyiv, 02002, Ukraine
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Kyiv, 03037, Ukraine
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Kyiv, 03049, Ukraine
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Kyiv, 04050, Ukraine
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Kyiv, 04210, Ukraine
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Uzhhorod, 88000, Ukraine
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Vinnytsia, 21018, Ukraine
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Vinnytsia, 21029, Ukraine
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Glasgow, G31 2ER, United Kingdom
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Leeds, LS7 4SA, United Kingdom
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Luton, LU4 0DZ, United Kingdom
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Staffordshire, WS11 5XY, United Kingdom