New monthly shot for schizophrenia enters early human testing

NCT ID NCT07484204

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial is testing a long-acting injectable form of the drug cariprazine, called AX251, in 48 adults with stable schizophrenia. The study aims to see how the drug moves through the body and whether it is safe when given as a single shot at different doses. If results are promising, it could lead to a more convenient treatment option that requires fewer doses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cariprazine (long-acting injectable)

What this could lead to

If successful, this could lead to a longer-lasting treatment option for schizophrenia, potentially reducing the need for daily pills.

What could go wrong

This is a very early Phase 1 study with only 48 participants, so safety and effectiveness are not yet known. The drug may cause side effects or not work as hoped.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ratandeep Multispeciality Hospital

    Nagar, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••