New Clot-Busting device could save lungs in emergency

NCT ID NCT05907564

First seen Feb 04, 2026 · Last updated May 14, 2026 · Updated 17 times

Summary

This study tests a new device called the Aventus Thrombectomy System to safely remove blood clots from the lungs in people with a sudden, severe pulmonary embolism. About 130 adults aged 18 to 80 with symptoms lasting less than two weeks will be enrolled. The goal is to see if the device improves heart strain and reduces serious complications like bleeding or death.

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Contacts and locations

Locations

  • Alexian Brothers Medical Center

    Elk Grove Village, Illinois, 60007, United States

  • Ascension Providence

    Southfield, Michigan, 48075, United States

  • Ascension Seton

    Austin, Texas, 78705, United States

  • Ascension St. John

    Tulsa, Oklahoma, 74006, United States

  • Ascension St. Vincent

    Indianapolis, Indiana, 46260, United States

  • Centennial Medical Center (HCA)

    Nashville, Tennessee, 37203, United States

  • CentraCare Heart and Vascular

    Saint Cloud, Minnesota, 56303, United States

  • El Camino Health

    Mountain View, California, 94040, United States

  • Emory University

    Atlanta, Georgia, 30322, United States

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Hartford Hospital

    Hartford, Connecticut, 06102, United States

  • Henry Ford Hospital

    Detroit, Michigan, 48202, United States

  • Holy Name Medical Center

    Teaneck, New Jersey, 07666, United States

  • Honor Health

    Scottsdale, Arizona, 85258, United States

  • Ichan School of Medicine at Mount Sinai

    New York, New York, 10019, United States

  • McLaren Health Care

    Bay City, Michigan, 48708, United States

  • Medstar

    Washington D.C., District of Columbia, 20010, United States

  • MemorialCare

    Long Beach, California, 90806, United States

  • NorthBay Medical Center

    Fairfield, California, 94533, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Ochsner Health

    New Orleans, Louisiana, 70121, United States

  • OhioHealth Research Institute

    Columbus, Ohio, 43214, United States

  • ProMedica - Jobst Vascular

    Toledo, Ohio, 43606, United States

  • Sutter Health

    Sacramento, California, 95816, United States

  • The Miriam Hospital

    Providence, Rhode Island, 02906, United States

  • University Hospitals

    Cleveland, Ohio, 44106, United States

Conditions

Explore the condition pages connected to this study.