Hormone clues: could a simple diet test unlock secrets of high blood pressure?

NCT ID NCT03484130

Ongoing Knowledge-focused Sponsor: Brigham and Women's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This study follows 100 adults aged 35-70 with mildly elevated blood pressure to see how their aldosterone hormone system changes over time. Participants will eat special high-salt or low-salt diets for a few days each year to test how their body responds. The goal is to better understand a condition called autonomous aldosterone secretion, which may contribute to high blood pressure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors better understand and identify early hormone-related causes of high blood pressure, potentially leading to more targeted treatments.
What could go wrong: This is an observational study, not testing a new treatment. It is small (100 participants) and early-stage, so findings may not apply to everyone or lead directly to new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

adrenal gland disorder hyperaldosteronism hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADRENAL GLAND DISEASE ALDOSTERONE DISORDER BLOOD PRESSURE

Contacts and locations

Locations

Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States

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