New drug duo aims to halt lung cancer growth

NCT ID NCT05017025

First seen Nov 19, 2025 · Last updated May 12, 2026 · Updated 22 times

Summary

This study tests whether adding an aurora kinase inhibitor to the standard drug osimertinib can better control advanced EGFR-mutant non-small cell lung cancer. About 32 adults with advanced or metastatic disease will receive the combination to find the safest dose and see if it slows tumor growth. The goal is to block enzymes that cancer cells need to multiply.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.