Can a statin tame a cancer protein? early trial seeks answers

NCT ID NCT03560882

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage study tests whether the cholesterol drug atorvastatin can reduce levels of a faulty protein (p53) in people with various cancers, including solid tumors and leukemia. About 50 participants will take atorvastatin for 1 to 4 weeks before their planned surgery or treatment. The main goal is to see if the drug lowers the abnormal protein, not to cure the disease.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia cancer hematopoietic and lymphoid system neoplasm myelodysplastic syndrome Myelodysplastic Syndromes neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Kansas Cancer Center - CRC

    Fairway, Kansas, 66205, United States