Can a common cholesterol drug fight cancer? new study explores atorvastatin's effect on mutant proteins

NCT ID NCT03560882

First seen May 07, 2026 · Last updated May 15, 2026 · Updated 4 times

Summary

This early-phase trial is testing whether the cholesterol drug atorvastatin can lower levels of a faulty protein (mutant p53) in people with solid tumors or relapsed acute myeloid leukemia. About 50 participants will take atorvastatin for 1 to 4 weeks before their planned surgery or treatment. The study aims to see if the drug changes the protein levels, not to cure the disease.

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Contacts and locations

Locations

  • University of Kansas Cancer Center - CRC

    Fairway, Kansas, 66205, United States

Conditions

Explore the condition pages connected to this study.