Could a common statin help beat tuberculosis?

NCT ID NCT06199921

Recruiting now Disease control Sponsor: Obafemi Awolowo University Teaching Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding atorvastatin, a widely used cholesterol-lowering drug, to standard tuberculosis (TB) antibiotics can help clear the infection faster and reduce lung damage. About 440 adults with pulmonary TB will receive either standard treatment alone or with different doses of atorvastatin for 16 weeks. Researchers will track safety, how quickly TB bacteria disappear from sputum, and lung function improvements over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Atorvastatin (a cholesterol-lowering drug) added to standard TB antibiotics
What this could lead to: If successful, adding atorvastatin could make TB treatment more effective, helping patients clear the infection faster and with less lung damage.
What could go wrong: This is a mid-stage trial, so results are not yet proven. The drug may not improve outcomes or could cause side effects like muscle pain or liver issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

pulmonary tuberculosis tuberculosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KOCH'S DISEASE PULMONARY TUBERCULOSIS TUBERCULOSIS

Contacts and locations

Locations

Bowen University Teaching Hospital
RECRUITING

Iwo, Osun State, 2345, Nigeria
Federal Medical Center
RECRUITING

Keffi, Nasarawa State, Nigeria
Federal Teaching Hospital
RECRUITING

Katsina, Katsina State, Nigeria
National Tuberculosis Reference Laboratory
RECRUITING

Zaria, Kaduna State, Nigeria
Obafemi Awolowo University Teaching Hospitals Complex
RECRUITING

Ile-Ife, Osun State, Nigeria
University College Hospital
RECRUITING

Ibadan, Oyo State, Nigeria
University of Abuja Teaching Hospital
RECRUITING

Gwagwalada, Nigeria
Usman Danfodio University
RECRUITING

Sokoto, Sokoto State, Nigeria

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