Could a common statin help beat tuberculosis?

NCT ID NCT06199921

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding atorvastatin, a widely used cholesterol-lowering drug, to standard tuberculosis (TB) antibiotics can help clear the infection faster and reduce lung damage. About 440 adults with pulmonary TB will receive either standard treatment alone or with different doses of atorvastatin for 16 weeks. Researchers will track safety, how quickly TB bacteria disappear from sputum, and lung function improvements over 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Atorvastatin (a cholesterol-lowering drug) added to standard TB antibiotics

What this could lead to

If successful, adding atorvastatin could make TB treatment more effective, helping patients clear the infection faster and with less lung damage.

What could go wrong

This is a mid-stage trial, so results are not yet proven. The drug may not improve outcomes or could cause side effects like muscle pain or liver issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pulmonary tuberculosis tuberculosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bowen University Teaching Hospital

    RECRUITING

    Iwo, Osun State, 2345, Nigeria

    Contact

    Contact Phone: •••-•••-••••

  • Federal Medical Center

    RECRUITING

    Keffi, Nasarawa State, Nigeria

    Contact

  • Federal Teaching Hospital

    RECRUITING

    Katsina, Katsina State, Nigeria

    Contact

  • National Tuberculosis Reference Laboratory

    RECRUITING

    Zaria, Kaduna State, Nigeria

    Contact Phone: •••-•••-••••

    Contact

  • Obafemi Awolowo University Teaching Hospitals Complex

    RECRUITING

    Ile-Ife, Osun State, Nigeria

    Contact

    Contact

    Contact

    Contact

    Contact

    Contact

    Contact

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  • University College Hospital

    RECRUITING

    Ibadan, Oyo State, Nigeria

    Contact Phone: •••-•••-••••

  • University of Abuja Teaching Hospital

    RECRUITING

    Gwagwalada, Nigeria

    Contact

  • Usman Danfodio University

    RECRUITING

    Sokoto, Sokoto State, Nigeria

    Contact Phone: •••-•••-••••

    Contact