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Can a new drug boost Semaglutide's power against diabetes and obesity?

NCT ID NCT07724340

Recruiting now Disease control Sponsor: Antag Therapeutics Source: ClinicalTrials.gov ↗

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This phase 2 trial tests whether adding an experimental drug called AT673 to the standard diabetes medication semaglutide leads to greater weight loss and better blood sugar control in adults with type 2 diabetes who are overweight or obese. Participants receive either a low or high dose of AT673 or a placebo, all alongside weekly semaglutide injections. The study aims to see if the combination is safe and more effective than semaglutide alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
an experimental drug called AT673 given alongside semaglutide
What this could lead to
If it works, this combination could offer a more effective option for weight loss and blood sugar management in people with type 2 diabetes.
What could go wrong
This is an early phase 2 trial with only 150 participants, so results may not apply broadly. AT673 is experimental, and its safety and added benefit over semaglutide alone are not yet known.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADULTS WITH OVERWEIGHT/OBESITY AND TYPE 2 DIABETES

Contacts and locations

Locations

  • CenExel Anaheim

    RECRUITING

    Anaheim, California, 92801, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CenExel Atlanta

    RECRUITING

    Atlanta, Georgia, 30331, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CenExel Decatur

    RECRUITING

    Decatur, Georgia, 30030, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CenExel Hollywood

    RECRUITING

    Hollywood, Florida, 33024, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CenExel Phoenix

    RECRUITING

    Chandler, Arizona, 85224, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CenExel SLC

    RECRUITING

    Salt Lake City, Utah, 84107, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CenExel Savannah

    RECRUITING

    Savannah, Georgia, 31405, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CenExel Tampa

    RECRUITING

    Tampa, Florida, 33613, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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