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Inhaled powder could offer rapid migraine relief without needles

NCT ID NCT07646613

Recruiting now Symptom relief Sponsor: Aspeya, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 22, 2026 · Updated 2 times

Summary

This study tests an investigational inhaled medication called ASY202 (dihydroergotamine dry powder) for treating migraine attacks in adults. Participants use a handheld inhaler to take the drug or a placebo during separate migraine episodes, and neither they nor the study team know which is which. The goal is to see if ASY202 can stop headache pain and bothersome symptoms like light sensitivity or nausea within two hours. The trial involves about 108 people and lasts around 16 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
dihydroergotamine (DHE) inhaled dry powder
What this could lead to
If successful, this could provide a fast-acting, non-injectable option for treating migraine attacks at home.
What could go wrong
This is an early-phase trial with only 108 participants, so results may not apply to everyone. Inhaled DHE may cause side effects like throat irritation or nausea.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

migraine disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MIGRAINE

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Clinical Neuroscineces Solutions

    NOT_YET_RECRUITING

    Orlando, Florida, 32806, United States

    Contact Email: •••••@•••••

  • Clinical Neuroscineces Solutions - Orlando

    NOT_YET_RECRUITING

    Orlando, Florida, 32801, United States

    Contact Email: •••••@•••••

  • Clinical Research Associates, Inc.

    NOT_YET_RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact Email: •••••@•••••

  • Highland Research

    NOT_YET_RECRUITING

    Salt Lake City, Utah, 84124, United States

    Contact Email: •••••@•••••

  • M3 Wake Research - Las Vegas Rainbow

    NOT_YET_RECRUITING

    Las Vegas, Nevada, 89118, United States

    Contact Email: •••••@•••••

  • Sunwise Clinical Research, Llc

    RECRUITING

    Walnut Creek, California, 94596, United States

    Contact Email: •••••@•••••

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