Inhaled powder could offer rapid migraine relief without needles

NCT ID NCT07646613

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an investigational inhaled medication called ASY202 (dihydroergotamine dry powder) for treating migraine attacks in adults. Participants use a handheld inhaler to take the drug or a placebo during separate migraine episodes, and neither they nor the study team know which is which. The goal is to see if ASY202 can stop headache pain and bothersome symptoms like light sensitivity or nausea within two hours. The trial involves about 108 people and lasts around 16 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

dihydroergotamine (DHE) inhaled dry powder

What this could lead to

If successful, this could provide a fast-acting, non-injectable option for treating migraine attacks at home.

What could go wrong

This is an early-phase trial with only 108 participants, so results may not apply to everyone. Inhaled DHE may cause side effects like throat irritation or nausea.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

migraine disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Highland Research

    NOT_YET_RECRUITING

    Salt Lake City, Utah, 84124, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • M3 Wake Research - Las Vegas Rainbow

    NOT_YET_RECRUITING

    Las Vegas, Nevada, 89118, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sunwise Clinical Research, Llc

    RECRUITING

    Walnut Creek, California, 94596, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••