Scientists decode genetic clues in rare bone marrow cancer
NCT ID NCT05710211
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how specific genetic changes (ASXL1 mutations) affect the course of myelofibrosis, a rare bone marrow cancer. Researchers will analyze blood and bone marrow samples from 50 adults to identify different patterns of these mutations. The goal is to better predict how the disease will progress and guide future treatments.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AP-HP Hôpital Saint Louis
NOT_YET_RECRUITINGParis, 75010, France
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CH Cholet
NOT_YET_RECRUITINGCholet, France
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CH de Cornouaille
NOT_YET_RECRUITINGQuimper, France
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CH de Vannes
NOT_YET_RECRUITINGVannes, France
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CHRU Brest
NOT_YET_RECRUITINGBrest, France
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CHRU Tours - Hôpital Bretonneau
RECRUITINGTours, France
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CHU Angers
RECRUITINGAngers, France
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CHU Henri MONDOR
RECRUITINGCréteil, 94010, France
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CHU Lyon
RECRUITINGPierre-Bénite, 69495, France
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CHU Nantes
NOT_YET_RECRUITINGNantes, France
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CHU de Bordeaux
RECRUITINGPessac, 33604, France
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Hôpital Bicêtre
RECRUITINGParis, France
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Institut Paoli Calmettes
RECRUITINGMarseille, 13009, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a new daily pill shrink the spleen and ease myelofibrosis symptoms?
- Can a new pill tame myelofibrosis?
- MRI as a window into bone marrow disease: a new biomarker test?
- Can a menin inhibitor tame myelofibrosis when standard drugs fall short?
- Can a drug free myelofibrosis patients from frequent blood transfusions?
- Heart safety check for new myelofibrosis drug in healthy volunteers